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Chapter 17

Lecture Outline
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Food Guide Pyramid
• What is it?
- dietary guidelines of what and how much
food should be eaten to remain healthy
- bases on age, gender, activity level
- www.mypyramid.gov
- includes grains, vegetables, fruits, fats, oil,
dairy, meat, beans

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Dairy
Fruits
Grains

Vegetables
Proteins

ChooseMyPlate.gov
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Kilocalories
• Calorie (cal):
amount of energy required to raise the temp.
of 1 gram of water 1o C

• Kilocalorie (kcal):
1000 calories

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Types of Nutrients
• Carbohydrates
• Proteins
• Lipids

• All are organic compounds.

• All contain carbon and hydrogen.

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Characteristics of Carbohydrates
• Contain C, H, O

• H:O is a 2:1 ratio


Ex. C6H12O6

• Broken down into monosaccharides.

• Monosaccharide:
- simple sugar (1 sugar)
- Ex. Glucose and fructose 7
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• Disaccharide:
- 2 sugars
- Ex. Glucose + fructose = sucrose
- Ex. Glucose + galactose=lactose

• Polysaccharide:
- many sugars
- Ex. Starch, grain, vegetables, glycogen, etc.

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Types of Carbohydrates
• Simple:
- no nutritional value
- cause weight gain
- Ex. candy and soft drinks (9 tea. sugar)
- Recommended amount: sparingly

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• Complex:
- fiber helps decrease colon cancer and heart
disease
- Ex. whole grains, pastas, rice, bread
- Recommended amount: at every meal
- Serving 1 piece of bread, ½ cup uncooked pasta

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Functions of Carbohydrates
• Short-term energy storage

• Converted to glucose quickly

• Glucose is used to make ATP (energy)

• Brain cells require glucose

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Characteristics of Proteins
• Contain C, H, O, N

• Broken down into amino acids

• 20 different amino acids

• Amino acids aren’t stored so a daily supply is required

• Recommended amount: 1-2 servings dairy group; 1-3


servings nuts/beans; 0-2 servings fish, poultry, eggs; red
meat sparingly
• Serving 2-3 oz. 12
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Types of Amino Acids
• Essential Amino Acids:
- 9 of 20 a.a.
- get from diet
- Ex. Tryptophan, valine, leucine, lysine, etc.

• Nonessential Amino Acids:


- 11 of 20 a.a.
- body makes them
- Ex. Glycine, proline, serine, etc. 13
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Food Sources for Amino Acids
• Complete food sources:
- supply all essential a.a.
- Ex. Red meat, milk, eggs, fish, poultry

• Incomplete food sources:


- supply only a few a.a.
- Ex. Beans, seeds, nuts, grains, leafy green
veg.
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Functions of Proteins
• Used to make skin, hair, nails, muscles

• Hemoglobin

• Act as enzymes

• Immune system functions

• Muscle contractions (actin and myosin)

• Part of cell membrane 15


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Characteristics of Lipids
• Contain C, H, O

• No 2:1 ratio of H:O

• Insoluble in water

• Ex. Fats, oils, cholesterol, triglycerides,


phospholipids

• Broken down into glycerol and fatty acids16


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Types of Lipids
• Unsaturated:
- “better” for us
- liquid at room temp.
- Ex. plant oils

• Saturated:
- “bad” for us
- solid at room temp.
- Ex. meat, fish, and dairy

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• Trans:
- processed fats and oils
- raise LDL and lower HDL
- increase heart disease

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Cholesterol
• What is it?
- steroid
- high conc. in brain, liver, egg yolks, whole milk,
cheese, butter, meats

• LDL cholesterol:
- low density lipoprotein
- “bad” cholesterol
- carries cholesterol from liver to cells
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• HDL cholesterol:
- high density lipoprotein
- “good” cholesterol
- carries cholesterol from cells to liver
(processed)
- increase HDL through exercise

• Normal cholesterol 180 mg/dL

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Lipids and Diet
• Recommended amount:
- sparingly for saturated fats
- cholesterol 300 mg/day (1 egg yolk)

• Why are fats/lipids bad?


- cause weight gain and heart disease
- increase risk of colon and pancreatic cancer

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Reducing Fat and Cholesterol

• Eat poultry, fish, and beans


• Eat vegetables and fruits high in fiber
• Use herbs and spices for seasonings
• Remove skin
• Broil, bake, grill
• Limit creams and butter
• Avoid processed cheese, egg yolks, liver
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Functions of Lipids
• Long term energy storage

• Insulates against heat loss

• Protective cushion for organs

• Cholesterol is part of cell membrane structure

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Table 17.1

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Vitamins
• Organic molecules in small quantities in food
needed for metabolism

• Balance diet gives body variety of vitamins

• Absence of vitamins results in deficiency


diseases

• Fat or water soluble


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Daily Values
• Appear on food labels to help people eat healthy

• Based on 2000 kilocalorie diet

• 60% carbs, 30% total fats, 10% sat. fats, 10%


proteins

• Used to calculate Percent Daily Value


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Figure 17.2

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Metabolism
• What is it?
- all chemical reactions in the body
- includes catabolism and anabolism

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Types of Metabolism
• Anabolism (synthesis):
- energy-requiring process
- Ex. ADP + P  ATP

• Catabolism (decomposition):
- energy-releasing process
- Ex. ATP  ADP + P

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Figure 17.3

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ATP
• Adenosine Triphosphate

• Energy carrier

• Energy is released when ATP is broken down

• Made in mitochondria

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Background for Aerobic Respiration
• Cytoplasm:
jelly-like fluid inside cell

• Mitochondria:
- produce ATP
- contain inner and outer compartments (cristae)

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• What are some other names for aerobic
respiration?
- cellular metabolism
- cellular respiration
- aerobic metabolism

• What is aerobic respiration?


breakdown of glucose in the presence of O 2
(ATP produced)

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• Where does aerobic respiration occur?
all cells

• What is the equation for aerobic respiration?


C6H12O6 + 6O2 + 38 ADP + 38 P  6CO2 + 6H2O + 38 ATP

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• What is glucose?
C6H12O6 (sugar)

• Where do we get glucose?


food (especially carb.)

• Why do we need glucose?


to make ATP

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• What are the steps in aerobic respiration?
1. Glycolysis
2. Prep Step
3. Citric Acid Cycle
4. Electron Transport Chain

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Glycolysis
• What is glycolysis?
- 1st step
- 10 step enzyme driven reaction

• Where does it occur?


cytoplasm

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• What happens?
C6H12O6 is broken down into 2 pyruvic acid (C 3)

• What are the products?


2 pyruvic acid (C3)
2 ATP
2 NADH

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• What are NAD+ and FAD?
- electron carriers
- from niacin and riboflavin

• Is O2 required?
no

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Prep Step (Acetyl-CoA Formation)
• What is the prep step?
2nd step

• Where does the pyruvic acid formed in


glycolysis go? (Where does it occur?)
into mitochondria

• What happens to the pyruvic acid?


each loses a carbon (C3 – C1= C2)
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• What happens to the carbon that came off
pyruvic acid?
C1 + O2  CO2 (breathe out)

• What is the new C2 molecule?


acetyl

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• What happens to acetyl?
combines with coenzyme A to form acetyl-CoA

• What are the products?


2 acetyl-CoA
2 CO2
2 NADH
0 ATP

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• Is O2 required?
yes

• Is ATP produced?
no

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Citric Acid Cycle
• What are some other names for the Citric
Acid Cycle?
Kreb’s Cycle

• What is it?
3rd step

• Where does it occur?


mitochondria 46
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• What happens?
acetyl + oxaloacetate  citric acid
C2 + C4  C6
• What are the products?
4 CO2
2 ATP
6 NADH
2 FADH2
• Is O2 required?
yes
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Electron Transport Chain
• What is the ETC?
4th step

• Where does it occur?


mitochondria’s inner and outer comp. (cristae)

• What are the beginning substrates (things


needed for the reaction)?
NADH and FADH2
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• What happens?
1.NADH and FADH2 carry their electrons/H+ to
inner mit. comp. and “drop” them off.
2.H+ passes through a H+ pump to outer mit. comp.
(more H+ outside than inside)
3.H+ diffuses back into inner mit. comp.
4.As H+ diffuses the reaction of ADP + P  ATP
occurs.
5.H+ combines with O2 to make H2O.
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• What are the products?
34 ATP
6 H2O

• Is O2 required and if so WHY?


Yes, so H+ can diffuse and ATP can be
produced

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Anaerobic Respiration

• What is anaerobic respiration?


breakdown of glucose in the absence of O2

• Where does it occur?


cytoplasm

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• What are the steps?
1. Glycolysis
2. Product formation

• What are the products?


2 lactic acid

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• How many ATP are produced?
2

• Who can perform anaerobic respiration?


animals, bacteria, yeast

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Humans and Anaerobic Respiration
• Occurs in muscles during vigorous exercise:
- if not enough O2 gets to the muscle then
anaerobic resp. occurs
- lactic acid builds up in muscles
- once O2 is available lactic acid is converted
back to pyruvic acid and aerobic resp. takes
place

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Lipid Metabolism
• Triglycerides are body’s main energy storage
molecules
• Between meals triglycerides are broken down
into fatty acids and glycerol
• Metabolism occurs in mitochondria
• Series of reactions where 2 Carbons are
removed for fatty acids to form acetyl-CoA
• Acetyl-CoA combines to form ketones
• Too many ketones leads to acidosis in blood

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Protein Metabolism
• Proteins are digested into amino acids
• Amino acids are taken up by liver
• Amino acids are used to make needed proteins
• Amino acids can be converted into pyruvic
acid and acetyl-CoA
• Metabolism results in ammonia which is
converted to urea (liver)

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Figure 17.8

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Metabolic States
• Absorptive state:
- period immediately after a meal
- nutrients absorbed through intestinal wall
into circ. and lymphatic systems
- 4 hours after meal
- glucose goes to cells and some glycogen and fat
- fats into adipose
- amino acids used in protein synthesis
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• Postabsorptive state:
- late in morning, late afternoon, or night after
absorptive state
- blood glucose levels maintained by converting
molecules to glucose
- first source glucose is liver
- triglycerides converted to glucose
- amino acids converted to glucose

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Metabolic Rate
• What is it?
- total amount of energy produced and use in
body per unit of time
- basal metabolic rate: energy needed to keep
resting body functional
- used to determine amount of kilocalories
need per day

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Body Temperature Regulation
• Average body temp. is 98.6o F

• Maintained by balancing heat input with heat


loss

• Radiation:
- gain or loss of heat as infrared energy
between 2 objects not in physical contact
- Ex. Sun, hot sand, snow 65
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• Conduction:
- exchange of heat between objects that in
direct contact
- Ex. Bottom of feet and ground
• Convection:
- transfer of heat between body and air or water
- Ex. cool breeze over body
• Evaporation:
- conversion of water from liquid to gas
- Ex. Water from body surface
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• Amount of heat exchanged between env’t and
body is determined by difference in temps.

• Temp. regulation occurs by dilation and


constriction of blood vessel in skin

• Type of negative feedback system

• Monitored by neurons in hypothalamus


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