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OBJECTIVES:
1. To explain what coarse dispersions are and their characteristics.
2. To study the influence of suspending agent on the sedimentation
parameters in a suspension.
A pharmaceutical suspension
is a coarse dispersion in which
internal phase ( therapeutically
active ingredient ) is dispersed
uniformly throughout the
external phase.
Emulsions
S. NO. INGREDIENT A B C D
ALUMINUM
1 2.5 g 2.5 g 2.5 g 2.5 g
HYDROXIDE
SODIUM
2 100 mg 100 mg 100 mg 100 mg
BENZOATE
XANTHAM
3 ------ 50 mg 100 mg 200 mg
GUM
DISTILLED
4 50 mL 50 mL 50 mL 50 mL
WATER
DATA AND RESULTS:
A Vo B Vu C D
1 10:16 am O min 0 mL 50 mL
2 10:31 am 15 min 10 mL 50 mL
3 10:46 am 30 min 12 mL 50 mL
4 10:51 am 45 min 12 mL 50 mL
5 11:06 am 1 hr. 12 mL 50 mL
12.5
Data/Observations
12
11.5
VOLUME OF SEDIMENT,F
11
10.5
10
9.5
9
15 mins 30 mins 45 mins 60 mins
TIME (mins)
CONCLUSION
ILLUSTRATION: