Beruflich Dokumente
Kultur Dokumente
B. Professionalism
C. Commitment
D. Unity
PRESIDENTS
Charlemagne T. Tamondong Nardito D. Moraleta
(1963-1967- UP Inst. Of Hygiene) (1967-1970-FEU)
• Infective Dose
• Stability of Environment
• Host Range
• Endemic Nature
Routes of Transmission
1. Direct skin, eye or mucosal membrane exposure to
an agent
2. Parenteral inoculation by a syringe needle or other
contaminated sharps or bites from infected animals
and arthropod vectors
3. Ingestion of liquid suspension of an infectious agent
or by contaminated hand to mouth exposures
4. Inhalation of infectious aerosols
Genetically Modified Agents
• NIH Guidelines are the key reference in assessing risk
and establishing an appropriate biosafety level for
work involving recombinant DNA molecules
• Viability in an aerosol
• Aerosol concentration
• Particle size
Approach to Assess Risks and Select Appropriate Safeguards
• Handwashing Facility
Biosafety Levels
• Biosafety Level 1 practices, safety equipment and
facility design and construction are appropriate for
undergraduate and secondary educational training
and teaching laboratories in which work is done with
defined and characterized strains of viable MO not
known to consistently cause disease in healthy
adult.
• B.subtilis, Nigeria gruberi, infectious canine hepatitis
virus and exempt organism
Biosafety Level 2
• BSL2 practices, equipment, and facility design and
construction are applicable to clinical , diagnostic,
teaching and other laboratories in which work is
done with broad spectrum of indigenous moderate-
risk agents that are present in the community and
associated with human disease of varying severity
• HBV, HIV, the Salmonella and Toxoplasma
Biosafety Level 3
• BSL2 practices, equipment, and facility design and
construction are applicable to clinical , diagnostic,
teaching, research or production facilities in which
work is done with indigenous or exotic agents with a
potential for respiratory transmission and which may
cause serious and potentially lethal infection
• M.tuberculosis, St.Louis encephalitis and coxiella
burnetti
Biosafety Level 4
• BSL4 practices, safety equipment, and facility design
and construction are applicable for work with
dangerous and exotic agents that pose a high
individual risk of life-threatening disease
• Marburg virus, Congo-crimean hemorrhagic fever
• Animal Facilities
• Clinical Laboratories