You are studying a rare autosomal recessive human disease that is fully penetrant in adults.

You
have identified a restriction fragment length polymorphism (RFLP) that is 10 map units from the
disease gene. Individual D is too young to show the disease trait. Show your work and define any
symbols used.

a) Using the pedigree above and ignoring the RFLP data, what is the probability that individual D
will be affected by the disease as an adult?

b) Considering all the data, give the genotypes for the individuals F, C and E as completely as
possible.

c) Considering all the data, what is the probability that individual D will be affected by the disease
as an adult?