Spotters

Gen. Pharmacology, ANS

1. MENTION ONE DRUG HAVING NARROW
THERAPEUTIC INDEX PHENYTOIN
2. HOW TO MONITOR DRUG DOSAGE FOR THE SAID
DRUG? TDM
COMPARE DRUGS B & D IN TERMS OF EFFICACY WITH
RESPECT TO DRUG A

DRUG ‘B ‘ IS EQUALLY EFFICACEOUS AS DRUG ‘A’

DRUG ‘ D’ IS LESS EFFICACEOUS THAN DRUG ‘ A’
1. What is effect of drug C on drug A
2. Give one example

Noncompetitive antagonism
Diazepam- Bicuculine
Compare drugs B & D in terms of potency with
respect to Drug A

Drug D is more potent than

Drug A
Drug B is less potent than Drug
1. What is effect of Drug B on Drug A?
2. Give one example

Competitive
Antagonism
d TC with ACh
1. What is black box warning?
2. What is the black box warning for the
use of sodium valproate in children < 3
years of age. FULMINANT HEPATITIS
1. Mention the drug that can cause this effect
THALIDOMIDE
2. Mention one current indication for this drug
ENL, CANCER CACHEXIA
1. Mention two drugs
which acts by this
mechanism
THYROXINE, VIT D
2. What is the relation
between this
mechanism of action
and onset of effect
DELAYED ONSET
1. Mention one drug example each which
follows A & B type of elimination kinetics
2. What happens to clearance of the drug ‘a’
when the dose is increased?

A B

1. A- ETHYL ALCOHOL, B- ANY DRUG

CLEARANCE DECREASES
1. What is this effect called as ?
2. Mention two drugs producing such effect

Repeated administration
of drug

TACHYPHYLAXIS
TYRAMINE, AMPHETAMINE. EPHEDRINE,
DOBUTAMINE
1. Identify this drug delivery system
2. Mention two drugs administered by using
this device

INFUSION PUMP
INSULIN, DOBUTAMINE , DOPAMINE
 1. Identify the naturalBotulinum
toxin X
Toxin
To prevent facial
2. Mention one usewrinkles
for it

Inhibition
X
Pheochromocytoma
1. What can happen if
the patient is
administered
propranolol without
any other medication
HYPERTENSIVE
EMERGENCY
2. Name a drug that
must be given before
giving propranolol
PHENTOLAMINE
1. Name the drug obtained from this
source.
2. Mention 2 of its uses.
Atropine
Preanaesthetic
medication
OP Poisoning
X 1. Identify drug X
Norepinephrine

2. Explain its effect

on pulse rate
Reflex bradycardia
X
Adrenaline
2. Mention one
use of the drug
Anaphylactic
Shock
ANGLE CLOSURE GLAUCOMA
1. Name a drug that
may be used both
orally & IV for this
condition.

2. Name one more

condition for which
it may be used

1.Acetazolamid
e
2.Acute
Mountain
 1. Identify the toxin being usedd-TC
here
2. Name the shortest acting drug with
Neostigmine
similar mechanism of action
 1. Mention a drug used for treatment
2. Identify drug X used in diagnosis

Myasthenia
Gravis

Pyridostigmine
Edrophonium

Before drug X After drug X

 as an
O.P.Compound
insecticide (Malathion)
2. Name one antidote used in its
poisoning Atropine
1. Name one neuromuscular blocker
used for this procedure?
Succinylcholin
2. Mention one adverse
e effect for
the drug usedMivacurium
1. Identify Drug X Competitive N.M.Blocker
2. Name a drug to reverse its action
Neostigmine
ACh Na

Drug X
ACh
 1. Name a drug used prior to this
test.
2. What is its duration of action?
2
Homatropine /
Cyclopentolate
3-7days/ 1 day