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Bipolar Disorder
Depressed
Mixed
Epidemiology
Lifetime prevalence
Type I - 0.7 - 0.8%
Type II - 0.4 - 0.5%
– Equal in males and females
– Increased prevalence in upper
socioeconomic classes
Age of Onset
– Usually late adolescence or early
adulthood. However some after age 50.
Late onset is more commonly Type II.
Genetics
Infectious
Neurosyphilis
HIV
Endocrine
Hyperthyroidism
Cushing’s Disease
Treatment
Education and Support
Medication
Acute mania
Lithium, Carbamazepine, Valproate,
Lamotrigine, antipsychotics,
benzodiazepines