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2. CHF 4. Constipation
Concentration:
◦ mg/mL
◦ mg/tab
◦ mg/cap
Basic Pharmacologic Dosaging
Formula:
◦ First get the patient weight
◦ Then identify the desired dose
Volume on hand (mL)
Patient weight (kg) x Desired dose x _________________
Concentration(mg)
=
Volume to administer (mL)
__________________________________
Frequency of administration
(times/day)
URTI/URI
Nonspecific URIs
◦ Acute, mild, lasts about 1 week
◦ Symptoms of rhinorrhea, nasal congestion,
sore throat, cough, hoarseness, body malaise,
sneezing, fever
◦ Antibiotics generally not indicated, only
symptom-based approach
URTI/URI
Sinusitis
◦ Usually maxillary sinus
◦ Acute sinusitis: if <4 weeks
◦ S/Sx: nasal drainage, congestion, facial pain on
pressure, headache, thick purulent nasal
discharge, tooth pain, pain when supine or
leaning forward
◦ Usually if <7 days = viral
URTI/URI
Sinusitis
◦ Tx:
1. decongestants: phenylephrine, phenylpropanolamine
containing medicines
2. Initial therapy:
1. Adult: Amoxicillin 500 mg PO TID or TMP-SMX PO BID
x 7 days
2. Pedia: Amoxicillin 50 mg/kg/day in 3 divided doses for 7
days
3. If showing resistance:
1. Adult: Coamoxiclav 500mg/125mg tab 3 times/day for 7
days
2. Pedia: Coamoxiclav 50mg/kg/day in three divided doses
for 7 days
URTI/URI
Acute Tosillopharyngitis
◦ Clinical suspicion of Streptococcal pharyngitis
(common cause of Rheumatic Heart Disease) –
fever, tinsillar swelling, exudates, enlarged/tender
anterior cervical lymph nodes, absence of cough
◦ Tx:
1. Initial therapy:
1. Adult: Amoxicillin 500 mg PO BID or TMP-SMX PO BID
x 7 days or Erythromycin 250 mg PO qID x 7 days
2. Pedia: Amoxicillin 50 mg/kg/day in 3 divided doses for 7
days
2. Nonpharma: Oral rinse, oral fluid intake, avoidance
of citrus irritants and sweets,
3. If with severe dysphagia: adult: single dose of 20 mg
Prednisone
URTI/URI
Otitis Media
◦ Acute onset of middle ear inflammation/loss of cone of light,
fever, otalgia, decreased hearing, tinnitus, erythematous tympanic
membrane
◦ Tx:
1. Initial therapy:
1. Adult: Amoxicillin 80 mg/kg/day in two to three divided doses
or Cefuroxime 30 mg/kg/day BID or Erythromycin 500 mg PO TID x 7 days
1. Pedia: Amoxicillin 60 mg/kg/day in 3 divided doses for 7 days or
Erythromycin 30 mg/kg/day in 3 divided doses x 7 days
2. If showing resistance:
1. Adult: Coamoxiclav 500mg/125mg tab 3 times/day for 7 days or Ceftriaxone
50 gm/kg/day IM in 2 divided doses for 3 days ( )ANST
2. Pedia: Coamoxiclav 50mg/kg/day in three divided doses for 7 days
3. Non-Pharma: increased fluid intake, cough etiquette
URTI/URI
Otitis Externa
◦ Swimmer’s ear
◦ Furunculosis on the outer third of ear canal,
severe otalgia especially on ear manipulation,
fever, white clumpy discharge --- specially if
swimmer, ear pruritus
◦ Therapy:
1. Adult/Pedia: Polymyxin B + Neomycin + hydrocortisone
or Ofloxacin otic drops (3%) otic solution 2-3 drops 3
x/day for 7-10 days
2. Avoid ear manipulation
3. Avoid swimming
LRTI
Bronchitis
Community Acquired Pneumonia
Pulmonary Tuberculosis – for special
session
Bronchitis
Fever, chills, sweats, cough, (either
nonproductive or productive of mucoid,
purulent, or blood tinged sputum), pleuritic
chest pain, dyspnea
Treatment:
Warm compresses ay makakatulong sa pagpapahinog ng pigsa
Ang Drainage o pagpiga ng pigsa ay dapat gawin at epektibo
lalo na sa malalaking pigsa
Antibiotic ointment sa mga kalat at basang sugat na infected,
at oral antibiotic din lalo na sa marami, malalaki at paulit-ulit
na pigsa
Furuncle/ Boil
Folliculitis
Impetigo Contagiosa
Mga Dapat Malaman sa Impetigo
Direct contact o nasal carrier,
mukhang natuyong pulot (honey colored crust)
palaginang paliligo at pagsasabon at pag-iingat sa mga
sugat, kamot at gasgas sa balat na hindi mahawahan
pagpapanatili na maiksi ang kuko at paghuhugas ng
kamay
pagiwas sa mga mayroon nitong sakit
ginagamot ng mupirocin ointment o kung malala
naman ay mag erythromycin ointment na
pagpapainom ng cloxacillin o cefalexin
hugas paminsan ng agua oxinada/hydrogen peroxide
Cellulitis
Mga Dapat Malaman sa Cellulitis
infection sa ilalim ng balat na kumakalat sa
may taba
kadalasang mula sa sugat, paso, crack sa
balat, o mga nagdaan sa injection na hindi
malinis ang gawa
maaaring madalas sa mga diabetiko
binibigyan ng cloxacillin o co-amoxiclav sa
malalang kalagayan at
paracetamol/mefenamic kung masakit
Cradlecap Impetigo
Pagsusuri
Cradlecap vs impetigo
Cradle cap’, is caused by overactive oil
glands, and usually disappears by the first
year of age.
Treatment is by applying mineral oil or
baby oil after shampooing, and rubbing
the scales off with a soft brush. Cradle
cap is harmless and non-contagious, but
may itch.
Abscess
Viral Skin Diseases
Varicella
Measles
Herpes Zoster
Varicella
Mga Dapat Malaman sa Varicella
hawa mula sa ubo ng mayroong bulutong
mukhang patak ng tubig sa petal ng rosas
pinakanakakahawa 1-5 days bago lumitaw ang
rashes at nagpapatuloy hanggang limang araw
pagtapos matuyo ng lahat ng butlig
iiwasang mainfect ng bacteria at putukin ang mga
butlig, ibaba ang temperature
ang pawis at init ay mas nakakakati ng butlig,
pwedeng haplasan ng yelo para guminhawa
magbigay ng paracetamol sa lagnat, at
diphenhydramine sa kati, at antibiotic kung may
nadagdag na skin infection
Herpes zoster
Mga Dapat Malaman sa Herpes zoster
isang uri ng bulutong kadalasan sa matanda.
ito ay labis na masakit, mapula, at
pulu=pulutong sa isang hilera ng balat
ginagamot lamang ang sintomas na pananakit
at paglalagnat, maaari ding hangarin ang
pagpapaigsi ng duration ng sakit gamit ang
antiviral gaya ng acyclovir
pag-iwas na makahawa ng bulutong ay
mahalaga
huwag putukin dahilan ito ay maaaring
mainfect
Fungal Skin Diseases
Tinea (capitis, corporis, pedia, ungium,
versicolor)
Malassezia furfur (Tinea versicolor)
Jock’s Itch (tinea cruris)
Athlete’s Foot (tine pedis)
Ringworm (tinea corporis)
Treatment of choice of tinea unguium is
probably oral terbinafine daily for four
months.
Itraconazole and griseofulvin are also
effective but treatment times are longer, and
in the case of the much cheaper griseofulvin,
treatment failure is very common.
Scopulariopsis treatment may well require
avulsion of the nail followed by topical
and/or systemic azoles until a normal nail
grows.
Tinea capitis is fungal infection of the scalp mostly
seen in pre-school children (3-7 years of age), but can
also occur in adults. It is caused by group of fungi that
normally live on the skin (dermatophytes) but may
overgrow in certain circumstances. Tinea capitis may
present as itchy, scaling area of hair loss, black
dots (parts of broken hair in the scalp skin), yellow
crusts (favus) or rough, thickened inflamed area
(kerion). Lymph nodes on the sides of the back of the
neck may be enlarged.
Tinea capitis is contagious, so other family members
should be examined in suspected cases.
Therapy is by prescribed anti-fungals by mouth such
as griseofulvin or terbinafine for 4-6 weeks
Tinea Capitis Tinea capitis
Tinea
Mga Dapat Malaman sa Tinea Capitis
fungal infection sa ulo
bilog na paglalagas ng buhok, pangangati, at
black dot sa anit, at dandruff
ginagamot ng oral antifungal gaya ng
itraconazole at fluclonazole
maaring galing sa barbero na hindi
nagaalcohol ng gamit at ginupitan
Tinea corporis Tinea versicolor
Tinea
Mga Dapat Malaman sa Tinea
Versicolor
matatagpuang sakit sa balat kadalasan sa mga naninirahan sa
lugar a may mainit at maalinsangang panahon
makakatulong ang topical antifungal creams gaya ng nizoral
ointment o di kaya ang pagpapaligo ng shampoo na may
selenium sulfide (head and shhoulderS).
pwede ring painumin ng clotrimazole o ketoconazole at ang
pagpapahid ng agua oxinada ay maaaring makatulong
Hindi ito nakakahawa
Tinea corporis
Ito ay nakakahawa
Ang paggamot ay pareho sa versicolor
Tinatawag ding ringworm
Tinea unguium Tinea Unguium
Tinea
Mga Dapat Malaman sa Tinea Unguium
Pagkapal, pagputi, at paninilaw ng kuko
Kadalasan matatagpuan sa mga naglalaba o
sa mga laging babad sa tubig ang mga kuko
maaaring manggaling sa mainit, kulob, at
basang sapatos
gingamot sa kombinasyon ng oral
antifungal at topical antifungal
Tinea cruris Tinea Pedis
Tinea
Skin Infestations
Pediculosis
Scabies
Pediculosis capitis Pediculosis
Pediculosis
Scabies adult Scabies baby
Scabies
Scabies
Scabies at Pediculosis
Ang lisa ay nagdudulot ng labis na pangangati at
allergic reaction ng balat dahil sa laway na inilalabas ng
lisa.
Ito ay nakakahawa sa direktang contact
Ang gamot ay paggamit ng Scabicide soap gaya ng Dr.
Wong, o di kaya ng Permethrin soap, shampoo at
lotion
Mariing ipinararating sa mga pamilya na kung ang ka-
pamilya ay mayroon, dapat lahat na sila ay maggamot.
Hugasan at ibilad ng maigi ang mga unan aty kumot na
ginagamit, at huwag makisalo sa damit o headphones
ng mayroon nito para di na makahawa.
GUIDELINES ON THE
TREATMENT OF URINARY
TRACT INFECTIONS
Categories
Acute Uncomplicated Cystitis in Women
Acute Uncomplicated Pyelonephritis
Asymptomatic bacteriuria
UTI in Pregnancy
Recurrent UTI
Complicated UTI
UTI in Men
Acute Uncomplicated Cystitis in
Women
Sa hindi buntis pagitan ng 18-64 years old
Sintomas ng
◦ masakit o mahapding pag-ihi
◦ Madalas na pag-ihi
◦ Dugo sa ihi
◦ +/- pananakit ng likod o balakang
◦ +/- abnormal na discharge sa ari
Acute Uncomplicated Cystitis in
Women
Mga rekomendasyon:
◦ Hindi required magpa-urinalysis liban na lang kung
mayroon discharge o vaginal irritation
◦ Gamutan: Kahit alin sa mga sumusunod:
Cotrimoxazole 800/160 2x/day x 3 days
Ciprofloxacin 250 mg 2x/day x 3 days
Ofloxacin 200 mg 2x/day x 3 days
Cefuroxime 250 mg 2x/day x 3 days
Co-amoxiclav 625 mg 2x/day x 7 days
◦ Kung 65 years old o higit pa at wala namang ibang
sakit, maaari ding gamitin ang parehong gamutan
Acute Uncomplicated Cystitis in
Women
Mga rekomendasyon:
◦ Kung hindi gumaling sa 3 day therapy
Magpa-urinalysis
Kung sa labis nang 7 days na therapy ay hindi
gumagaling, ituring na COMPLICATED UTI
◦ Kung gumaling na, huwag nang ipa-urinalysis
Acute Uncomplicated
Pyelonephritis in Women
Sintomas ng
◦ Paglalagnat T>38C at/o pangangatog
◦ pananakit ng likod o balakang
◦ Pagkaliyo at pagsusuka
◦ URINALYSIS: >/= 5 wbc/hpf
◦ +/- masakit o mahapding pag-ihi
◦ +/ - Madalas na pag-ihi
◦ +/ - Dugo sa ihi
◦ +/- abnormal na discharge sa ari
Acute Uncomplicated
Pyelonephritis in Women
Dapat bang mag-admit? Hindi kailangan
kung:
◦ hindi buntis
◦ masunurin naman sa gamutan at marunong
magfollow up
◦ walang ibang kumplikasyon
◦ hindi labis na masakit ang balakang
◦ At labis na mataas ang lagnat
Acute Uncomplicated
Pyelonephritis in Women
Rekomendadong gamutan:
Ciprofloxacin 500 mg 2x/day x 7days
Ofloxacin 400 mg 2x/day x 14 days
Cefuroxime 500 mg 2x/day x 14 days
Co-amoxiclav 625 mg 3x/day x 14 days
◦ Hindi kaya ng Amoxicillin o Cefalexin
◦ Sinusubukan nang iiwas sa Cotrimoxazole
dahil sa mataas na resistance dito
Acute Uncomplicated
Pyelonephritis in Women
Rekomendadong gamutan:
◦ Kung sa pagitan ng 72 hours o 3 araw ay hindi
nawawala ang paglalagnat o umuulit o lumalala
ang sintomas, isipin ang posibilidad ng
Bato sa Bato (Kidneys)
Baradong Urinary tract
Abscess sa Bato
◦ Kung hindi pa rin gumaling, ipa-Culture na ang
Ihi para itama ang gamutan ayon sa mikrobyo
Asymptomatic Bacteriuria
UTI na walang sintomas liban na lamang sa
pagkakaroon ng moderate to many na
BACTERIA o >10 wbc/hpf SA (2)
Urinalysis
Mga nag-uurinalysis ng walang sintomasng
UTI ay ang mga:
◦ Ooperahan
◦ Renal transplant
◦ Diabetiko
Asymptomatic Bacteriuria
Mga rekomendasyon:
◦ Gamutan: Kahit alin sa mga sumusunod:
Cotrimoxazole 800/160 2x/day x 7 days
Ciprofloxacin 250 mg 2x/day x 7 days
Ofloxacin 200 mg 2x/day x 7 days
Cefuroxime 250 mg 2x/day x 7 days
Co-amoxiclav 625 mg 2x/day x 7 days
◦ Kung 65 years old o higit pa at wala namang
ibang sakit, maaari ding gamitin ang parehong
gamutan
Asymptomatic Bacteriuria in
Pregnancy
UTI na walang sintomas liban na lamang sa
pagkakaroon ng moderate to many na
BACTERIA o >5 wbc/hpf SA (2)
Urinalysis ng BUNTIS
Mga rekomendasyon:
◦ Routine urinalysis sa buntis 9-17th weeks AOG
Asymptomatic Bacteriuria
Rekomendadong gamutan:
◦ Nitrofurantoin (liban kung 3rd trimester)
◦ Coamoxiclav 625 mg 2x/day x 7 days
◦ Cefalexin 500 mg/cap 3x/day x 7 days
◦ Cotrimoxazole 800/160 2x/day x 7 days (liban
kung 1st and 3rd trimester)
Dapat na may follow up na urinalysis
Acute Cystitis in Pregnancy
Sintomas ng:
◦ Madalas na pag-ihi
◦ Di mapigilang pag-ihi
◦ Masakit o mahapding pag-ihi
◦ > 5 WBC o Bacteria sa urinalysis (+/- fever)
◦ CVA tenderness o pananakit ng balakang
◦ +/- Dugo sa ihi
Acute Cystitis in Pregnancy
◦ Gamutan: Kahit alin sa mga sumusunod:
Cotrimoxazole 800/160 2x/day x 7 days
Cefuroxime 250 mg 2x/day x 7 days
Co-amoxiclav 625 mg 2x/day x 7 days
◦ Mag follow up urinalysis
Acute Uncomplicated
Pyelonephritis in Pregnancy
Sintomas ng:
◦ Paglalagnat T>38C at/o pangangatog
◦ pananakit ng likod o balakang
◦ Pagkaliyo at pagsusuka
◦ URINALYSIS: >/= 5 wbc/hpf
◦ +/- masakit o mahapding pag-ihi
◦ +/ - Madalas na pag-ihi
◦ +/ - Dugo sa ihi
◦ +/- abnormal na discharge sa ari
Acute Uncomplicated
Pyelonephritis in Pregnancy
Suspected Case
Any individual, regardless of age, with the following signs
and symptoms:
• fever (38°C of more, or hot to touch); and
• Maculo-papular rash (non-vesicular)
• at least one of the following:
cough, coryza (runny nose) or
conjunctivitis (red eyes).
What are the Differential Diagnosis used to
Detect Cases?
Eczema
Mga Dapat Malaman sa Eczema
pamumula, pagkapal, pangangati ng balat
dahilan sa pagiging sensitibo o allergic
maaring mamaga o magbalat, at magluha
ito ay iniiwasang kamutin at magsugat para di
mainfect, panatilihin ang moisture ng balat
gamit ang lotion, at umiwas sa mga nakaka-
allergy
ipagtanong mabuti sa tuwing kailan
nagkakaroon
ang paggamot at topicallow dose steroid
cream gaya ng hyrocortisone cream o
clobetasol ointment
Lichen Simplex chronicus (late) Lichen Simplex chronicus (early)
Treatment:
◦ Bronchodilators: Salbutamol given every 4-8 hours, depending on
severity
◦ Inhaled corticosteroids: Fluticasone, budesonide
Bronchial Asthma
Treatment:
1. Supportive – antibiotics for bacterial superinfections
2. Vit A expecially for young children
3. MMR vaccine should have been given, 12-15 months, and at
school age children 4-12 years.
Diabetes Mellitus
Pathogenic hyperglycemia
S/Sx:
◦ FBS: >= 7.0 mmol/L or 126 mg/dL or RBS of
>=11.1 mmol/L or 200 mg/dL
◦ Polyuria, polydipsia, weight loss, fatigue,
weakness, blurred vision, frequent superficial
infecitons, poor wound healing
◦ History of overweight, poor exercise, smiking,
alcohol intake, family history of DM and Heart
disease
Diabetes Mellitus
Tx:
◦ Small frequent feedings, weight loss
◦ Pharma:
1. Metformin 500 mg-2500 mg 1-3x/day (avoid in
kidney and liver disease patients) – improves
lipid profile, weight loss, lowersi nsulin level,
does not cause fast hypoglycemia
2. Sulfonylureas: Glibenclamide/Gliclazide
3. Simvastatin 20 mg/tab OD at night if beyond
forty and specially if obese
4. Insulin
SPECIAL CLINICAL
CONSIDERATIONS
ADVERSE EVENTS FOLLOWING IMMUNIZATION
Bronchospasm, stridor,
collapse, hypotension,
dysrhythmias
ADVERSE EVENTS FOLLOWING IMMUNIZATION
HOW to DISTINGUISH ANAPHYLAXIS FROM FAINT
ONSET FAINT ANAPHYLAXIS
Skin Usually at the time or Within the first few
soon after the injection minutes after injection
Respiratory Pale, sweaty, cold, Red, raised and itchy
clammy rash; swollen eyes, face;
generalized rash
Cardiovascular Normal to deep breaths Noisy breahting from
airway obstruction
(wheeze or stridor)
Gastrointestinal Bradycardia Tachycardia
Transient hypotension Hypotension
Neurological Transient loss of Loss of consciousness,
consciousness, good little response once in
response once in prone prone position
position
ADVERSE EVENTS FOLLOWING IMMUNIZATION