Renal Neuroblastoma

Case Slide Reference Slide

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Figure 2. Case Slide A, Kidney, H&E Staining, 4x Figure X. Renal Neuroblastoma, H&E Staining, 4x [1]

Aggregates of small, basophilic cells adjacent to the renal medulla.

Abundant renal tubules in the renal medulla.Darkly-staining basophilic cells adjacent to renal medulla.
 Renal Neuroblastoma
Case Slide Reference Slide

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Figure X. Renal Neuroblastoma, H&E Staining, 10x

Figure 3. Case Slide B, Kidney, H&E Staining, 10x
[1]
Abundant renal tubules in the renal medulla. Abundant darkly-staining basophilic cells distributed in a diffuse pattern interspersed
by eosinophilic fibrous stroma.
Presence of darkly-staining basophilic cells distributed in a diffuse pattern infiltrating the renal parenchyma
 Renal Neuroblastoma
Case Slide Reference Slide

Photo here Photo here

Figure X. Renal Neuroblastoma, H&E Staining, 10x

Figure 4. Case Slide C, Kidney, H&E Staining, 10x
[1]
Abundant round darkly-staining basophilic cells in the background. Tubular-like structures with darkly-staining basophilic cells
Eosinophilic cells resembling red blood cells. Large darkly-staining basophilic cells forming a glomerular structure. Eosinophilic fibrous stroma with darkly-staining round
basophilic cells.
Nests of darkly-staining basophilic cells forming rosette pattern
 Renal Neuroblastoma
Points of Consideration in Ruling in Points of Consideration in Ruling out
Epidemiology Epidemiology
Male predominance with a ratio of 7:1 Commonly present in children 3 months to 3 years; rare beyond age
10
Clinical Presentation
Mild blood pressure elevation Histopathologic Features
Dull right back side pain Absence of collection of tumor cells forming Homer Wright rosettes
Mildly tender mass palpable in the right lumbar region

Histopathologic Features
Round to oval darkly staining basophilic cells with scant cytoplasm