APHASIA (2A)

CEPI RAMDHANI
NEUROPSYCHIATRY CLUB
FACULTY OF MEDICINE
PREFACE
Language = Speech + Toughts
Aphasia = IS A DISTURBANCE OF
LANGUAGE FUNCTION DUE TO THE
DAMAGE OF THE LANGUAGE CENTER IN
THE BRAIN.
 ETIOLOGY

AHA
JOURNAL
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asia_Attributable_to_20160730-19915-
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 PHATOPHYSIOLOGY

The center of traditional languages is the

BROCA MOTOR LANGUAGE CENTER and
the WERNICKE RECEPTIVE LANGUAGE
CENTER, which is usually located in the
dominant hemisphere (most often left).
ARCUATE FASCICULUS
 PHATOPHYSIOLOGY
Auditory input and language coding in the
SUPERIOR TEMPORAL LOBE, language
analysis in the PARIETAL LOBE and
expression in the FRONTAL LOBE.
 PHATOPHYSIOLOGY

CORTICOBULBAR
TRACT

CAPSULA INTERNA ->

BRAINSTEM
 PHATOPHYSIOLOGY
LAST MEANED AS A
COMPLETE LANGUAGE
WITH VOCABULARY,
MEANING OF SYNTHESIS,
AND GRAMATICAL IN
INTERCONNECTION
BETWEEN THE LANGUAGE
CENTERS

GANGLIA BASALIS AND

CEREBELLUM AS
MODULATOR EFFECTS
PHATOPHYSIOLOGY

APHASIA BROCA :
OCCLUSION MCA
SUP (M2 SUP)

APHASIA
WERNICKE :
OCCLUSION MCA
INF (M2 INF)

APHASIA GLOBAL :
MCA (M1 MAIN)
CLINICAL MANIFESTATION
 CLINICAL MANIFESTATION
ANOMIC, PARAPHASIA
WORD FINDING & NAMING FAILURE
FLUENCY : Precentralis Gyri
UNDERSTANDING : Sulcus ParietoOccipitalis
REPETITION : Sulcus Lateralis
 APHASIA CLASSIFICATION
A.Broca
A.Wernicke
A.Global
A.Transcortical :
Type 1 ( A.Dynamic )
Type II ( A.Suplementary Motor Area)
A.Anomic
A.Conduction
 A.Broca
- Aphasia C.M
- Hemipharesis (Due
to the broca area is
adjacent to the
gyrus presentralis
as primary motoric
center)
- Writing disorders (
Due to the broca
area is adjacent to
Exner Area as
writing center)
 A.Wernicke
- Aphasia C.M
 A.Global
- Verbal Apraxia
- Fluency is
interrupted by the
word production
being limited to
one or two words
that have no
meaning, even the
patient cannot
speak at all.
A.Transcortical
 A.Anomic
When
someone is
asked to say the
name of the
pen, the patient
will answer "the
object used to
write“
Quadranopia
 A.Conduction
ARCUATE
FASCICULUS
Damage
Able to pronounce
words smoothly
but many
paraphrase
mistakes
Cannot read aloud
but can read
 Differential Diagnosis
Severe dysarthria
Dementia
Psychosis
Hearing loss,
Aphemia / Mutism
 Supporting Investigation
CT, MRI, Angiography, Ultrasound of the
carotid and vertebral artery Doppler,
transcranial Doppler
 Treatment
Pharmacology
Pirasetam 480mg 2X/day 6wk-7mo
Donepezil 5mg 4wk, 10mg 12wk
Galantamin
Bifeleman
Fisostigmin
Non-Pharmacology
Speech Therapy
Neurorestoration
ARIGA-
THANKS
GOZAI-
MUCH