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Asthma is a common chronic
inflammatory disease of the airways
characterized by variable and recurring
symptoms, reversible airflow obstruction
and bronchospasm. Common symptoms
include wheezing, coughing, chest
tightness, and shortness of breath
INCIDENCE:
Hereditary
Allergens
Airpollutants
Upper respiratory tract infections
Drug over dosage
Occupational exposures
Environmental factors
Psychological factors
PATHOPHYSIOLOGY:
CLINICAL MANIFESTATIONS:
Wheezing
Cough
Chest tightness
Dyspone
Hypoxia
Nasal flaring
Sputum is thick and tenacious
Decreased or absence of breath sounds
called “SILENT CHEST”
SYMPTOMS:
ASSESSMENT AND DIAGNOSTIC
STUDIES:
History collection
Physical examination
Pulse oximetry
Pulmonary function test
Arterial blood gas
Complete blood count
Chest x-ray
MANAGEMENT:
Medications:
Bronchodilators:
-long acting beta adrenagic blockers:
eg:salmeterol,formeterol,theophylline
Anti-inflammatory drugs:
-corticosteriods:
eg:flunisolides,beclamethasone,cromolyn
-Mast cell stabilizers:
eg:montelukast,zileuton
DRY POWDER INHALERS
CORTICOSTEROIDS ARE
MOST EFFECTIVE
DELIVERY METHODS: