EPI Vaccines

• inactivated (killed) microorganisms

• uses the killed version of the microorganism that causes the disease
• attentuated microorganisms
• live microorganisms that have been altered so that they are no longer
pathogenic, but are still antigenic.
• fragments from microorganisms
• contains a small part or piece of the microorganism selected for its
ability to initiate a specific immune response
• toxoids
• made from the microorganism inactivated toxic compound
 VACCINE CONTENTS
BCG (Bacillus Calmette Guerine) Live, attentuated bacteria
Hepatitis B Vaccine RNA-recombinant, using Hepatitis B
surface antigen (HBs Ag)
DPT - HepB - Hib Diphtheria toxoid, inactived pertussis
(Pentavalent vaccine) bacteria, tetanus toxoid, recombinant
DNA surface antigen, and synthetic
conjugate of Haemmophilus
influenzae B bacilli
Oral Polio Vaccine Live, attenuated viruss (trivalent)
Anti-measles Vaccine (AMV1) Live, attenuated virus
Measles-Mumps-Rubella Vaccine Live, attenuated viruses
(AMV2)
Rotavirus Vaccine Live, attenuated virus
Tetanus Toxoid Weakened toxin
FORM
Freeze-dried, reconstituted with a
special diluent
Cloudy, liquid, in an auto disable
injection syringe if available
Liquid, in an auto-disable injectio
syringe
Clear, pinkish liquid
Freeze-dried, reconstituted with a
special diluent
Freeze-dried, reconstituted with a
special diluent
Clear, colorless liquid, in a container
with an oral applicator
Sometimes slightly turbid in
appearance; Clear, colorless liquid
Target Setting and Vaccine Requirements
• First specific goal of EPI: 100% immunization of infants/children
against the most common vaccine-preventable diseases
• Vaccine is calculated based on eligible populations.
• Formulas to estimated eligible population:
Estimated number of infants = Total population x 2.7%
Estimated number of 12-to-59 month old children
= total population x 10.8%
Estimated number of pregnant women = total population x 3.5%