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Obat-obat Pada Mata

Jimmy Posangi
Anti infeksi bakteri
Levofloxacin
Chloramphenicol
Dibecacin
Sulfacetamide
Fusidic acid
Ciprofloxacin
Gentamicin
Tobramycin
Tetracyclin
Oxytetracyclin
Gramicidin
Polymixin B
Ofloxacin
Neomycin
Framycetin
Five Basic Mechanisms of Antibiotic
Action against Bacterial Cells:
1. Inhibition of Cell Wall Synthesis
Beta-Lactams ---> Inhibition of
peptidoglycan synthesis (bactericidal)
2. Inhibition of Protein Synthesis
(Translation)
30S Ribosome site
Aminoglycosides ---> Irreversibly bind 30S
ribosomal proteins (bactericidal)
3. Alteration of Cell Membranes
Polymyxins (topical) ---> Cationic
detergent-like activity (topical use)
4. Inhibition of Nucleic Acid Synthesis
DNA Effects
Quinolones ---> Inhibit DNA gyrases or
topoisomerases required for supercoiling of
DNA; bind to alpha subunit
5. Antimetabolite Activity
Sulfonamides & Dapsone ---> Compete
with p-aminobenzoic acid (PABA)
preventing synthesis of folic acid
Antiseptic
Thimerosal
(pengawetan vaksin)
Antivirus

Iodoxuridine
Acyclovir
Stages of viral replication
John Goulding, Imperial College London, UK

1. attachment
2. penetration
3. uncoating
4. replication
5. assemby
6. virion release
Corticosteroid

Betamethasone
Hydrocortisone
Prednisolone
Fluorometholone
Dexamethasone
Metabolime Asam Arakhidonat
Bilayer Phopholipid Sel
Trauma
Infeksi
Neoplasma

Arachidonic
acid

Siklooksigenase COX-1 Lipooksigenase (LOX)


COX-2

Prostaglandin, PGE2, PGI2, PGF2α Leukotrin


Tromboxan
Antihistamin

Chlorpheniramine maleate
Pemirolast
Lodoxamide
Na cromoglycate
Midriatikum
Tropicamide
Scopolamin
Atropine
Homatropine
Phenylephrine
Miotikum

Betaxolol
Pilocarpine
Acetylcholine
Tropicamide
Pilocarpine
Scopolamin Phenylephrine Betaxolol
Acetylcholine
Atropine

Homatropine
Glaucoma

Brinzolamide
Betaxolol
Pilocarpine
Timolol
Latanoprost
Diuretics
MANNITOL
Proximal THIAZIDES
Convulated Tubule
Early Distal
Convulated Tubule

65%
10%

FUROSEMIDE 20% Spironolactone,


Thick Segment Triamterene
Ascending 1%-5%
Late Distal
Limb of Henle’s Convulated
Loop Tubule and
Collecting Duct
(Distal Nephron)
Supplement
Bilberry
Retinol
Vit E
Beta carotene
Tribulus terrestris
Lutein
Lycopene
Cataract
Pirenoxine
CaCl2 anhydrous
K iodide
Na thiosulfate
Phenylmercuric nitrate
Etildiamin tetra acetat (EDTA)
Antinyeri
Diclofenac
Tetracaine
Tears replacement/lubricant
Benzalkonium
Hypromellos
Iritasi/fatique
Tetrahydrozoline
Naphazoline
Oxymetazoline
Detect Foreign Body

Fluorecin