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Writing Medical Abstracts(5)

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(1 of 2)
(+) Radiation exposure increases the risk
of cancer among the general population, as evidenced by medical
radiation or radiation-contaminated environments such as 60Co
contaminated buildings, nuclear power plants, professional use of
radiation and radioactive substances. Given the complexity of radiation
exposure in Taiwan, more thoroughly understanding irradiation safety-
related issues is of priority concern. Despite the use of radiation
dosimetery for acute high dose exposure as an effective means of
estimating the exposure for individuals chronically exposed to ionizing
radiation over a protracted period, dose reconstruction for individuals
with previous long-term and low dose-rate radiation exposure has
seldom been examined, especially when attempting to assess
ionization radiation in order to define low dose rate exposures.
Exposure to high dosages of ionizing radiation may increase the
incident rate of various cancers. Therefore, this work presents a
low level dose mode method, capable of accurately predicting the
radiation dosage levels in the surrounding environment of a nuclear
power plant that could potentially harm humans.
(2 of 2)
Radiation dosage distribution and adverse health impact on
neighboring residents are estimated using the physics dose
mode method with simplified calculations of the mean and
standard deviation. Biological dose models are then used to
relate the location and biological effects to the controlled
exposure factor levels. Next, an optimal combination of process
parameters is obtained using the estimated risk dosage method.
Analysis results indicate that the proposed
low level dose mode method can analyze the dosage levels of
radiation among neighboring residents of a nearby nuclear
power plant. Analysis results of dosage levels inform residents
of the health impact of low level radiation, hopefully leading to a
lower dose rate and occurrence of cancer.
Importantly, the low level dose mode method enables medical
personnel to estimate the radiation dosage distribution among
neighboring residents near a nuclear power plant, providing a
valuable reference for governmental authorities in establishing
legislation to protect inhabitants from unsafe radiation levels.
(1 of 2)
(+) As i s wel l known, si l ver
nanoparticles have an affinity with a proteins thiol and amino
group. Surface plasma resonance (SPR), a biosensor, can
detect proteins because silver nanoparticles have a coating on
SPR, necessitating the ability to use SPR sensitively and
accurately to detect proteins. For instance, a protein containing
amyl oi d B-deri ved di f f usi bl e l i gands (ADDLs) causes
Alzheimers disease. Although local SPR (LSPR) is more
sensitive and accurate than the conventionally adopted SPR,
LSPR has many nanostructures, explaining why sensitivity and
accuracy are of priority concern. Moreover, the conventionally
adopted SPR is more expensive than LSPR. Therefore,
this work develops a sensitive and accurate biosensor that can
identify special proteins efficiently, as well as detect certain
diseases in their early stages. For instance, identifying the
protein ADDLs early can be used to diagnose Alzheimers
disease in its early stages so that therapeutic treatment can be
administered.
(2 of 2)
Nanoparticles are developed in a glass chamber, followed
by the design of a LSPR biosensor. The biomolecular structure
is then detected using LSPR, allowing us to identify the disease.
Analysis results indicate that the proposed
analytical method for detecting bio molecular structures can
detect solution consistency below 1pM with a high degree of
accuracy. Moreover, the proposed LSPR
biosensor provides a highly sensitive and accurate means of
detecting the bio molecular structure. The ability to identify the
disease in its early stages can lead to earlier treatment and
recovery. For instance, Alzheimers disease can be diagnosed
early because LSPR can detect ADDLs with a high degree of
sensitivity, ultimately increasing the survival rate of patients.
Further details can be found at
http://www.chineseowl.idv.tw

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