Burden of Cancer in Asia

The Burden of Cancer in Asia
2008 Pfizer Inc. All rights reserved.
Data Sources
GLOBOCAN 2002 International Agency for Research on Cancer (IARC) Descriptive Epidemiology Group World Health Organization (WHO) Statistical Information System (WHOSIS) 2005, 2006 World Health Organization International Data Base (IDB), 2008 United States Census Bureau Population Division Taiwan Cancer Registry, 2005 Taiwan
Demographic Characteristics
Distribution of Worldwide Population

US 5%
China 20%
Rest of World 47%
15 Asian Countries 48%
India 17% 13 Asian Countries 11%
Total Population = 6.7 Billion
Source: US Census Bureau, International Data Base 2008.

Distribution of Worldwide Male Population

US 4%
China 20%
Rest of World 47%

Distribution of Worldwide Female Population

US 5%
China 20%
Rest of World 48%

Total may not add to 100% because of rounding. Source: US Census Bureau, International Data Base 2008.
Demographic Characteristics by Country

Population Country Number (Millions)
14
1,338 1,148
Male (%)
49
51 52
Median Age (Years)

22
34 25
Proportion Less Proportion Than 15 Year 15 to 64 Years of Age (%) of Age (%)
33
20 32
Proportion 65 Years and Older (%)

4
8 5
Cambodia
China India
63
72 63
Indonesia
Japan Korea
238
127 48
50
49 50
27
44 37
28
14 17
66
65 72
6
22 11
Laos
Malaysia Mongolia Philippines Singapore Sri Lanka Taiwan Thailand Vietnam United States
7
25 3 96 5 21 23 65 86 304
50
50 50 50 49 49 51 49 50 49
19
25 25 22 38 30 36 33 27 37
41
32 28 36 15 24 17 21 26 20
56
63 68 60 77 68 72 70 69 67
3
5 4 4 9 8 11 9 6 13

Morbidity and Mortality: Incidence
Incidence Rates for Total Cancers in Males in Asian Countries and the United States
United States Mongolia
North Korea
China
South Korea South Korea
Japan
Pakistan India
Nepal Taiwan Burma Laos Vietnam Philippines
Rates per 100,000 95 104 105 144 145 214 215 410
Excludes non-melanoma skin cancer. Rate per 100,000. Age-standardized to the World Standard Population. Source: Taiwan Cancer Registry Annual Report 2005 (Taiwan); GLOBOCAN 2002, IARC (all other countries).
Sri Lanka Bangladesh
Thailand
Cambodia Malaysia
Bhutan Singapore
Indonesia
Incidence Rates for Total Cancers in Females in Asian Countries and the United States
United States Mongolia
North Korea
China
South Korea Pakistan India Burma Laos Vietnam Philippines Nepal Taiwan
Japan
Rates per 100,000 95 104 105 144 145 214 215 410
Excludes non-melanoma skin cancer. Rate per 100,000. Age-standardized to the World Standard Population. Source: Taiwan Cancer Registry Annual Report 2005 (Taiwan); GLOBOCAN 2002, IARC (all other countries).
Sri Lanka Bangladesh
Thailand
Cambodia Malaysia
Bhutan Singapore
Indonesia
Incidence Rates for Total Cancers by Gender and Country

Cambodia China India Indonesia Japan Korea Laos Malaysia Mongolia Philippines Singapore Sri Lanka Taiwan Thailand Vietnam United States 0 50 100 150 200 250 300 350 400 450 Males Females
Rate per 100,000

Excludes non-melanoma skin cancer. Age-standardized to the World Standard Population. Source: Taiwan Cancer Registry Annual Report 2005 (Taiwan); GLOBOCAN 2002, IARC (all other countries).
Cancer in Males
Lung cancer is the most common or second-most common cancer among males in all Asian countries but for India, Japan, Mongolia, and Taiwan Liver cancer has the highest incidence rate of any cancer in Laos, Mongolia, Taiwan, and Thailand Stomach cancer is the highest incident rate cancer in both Japan and Korea, and the second highest incident cancer in Cambodia, China, and Mongolia Cancer of the oral cavity is most common in India and Sri Lanka, but is among the top-five cancers for males in only 1 other country, Cambodia In the United States, prostate cancer is by far the highest incident cancer among males, occurring at twice the rate of lung cancer, the next highest
The prostate cancer rate in the United States exceeds the rates in each of the fifteen Asian countries
Cancer in Females
Breast cancer among females is the most common or secondmost common cancer in all but 3 of the Asian countries (China, Mongolia, and Thailand) Stomach cancer is the highest incident cancer among females in China and Korea; uterine cervix cancer is highest in Cambodia, India, Laos, Thailand, and Vietnam Breast cancer is also the most common cancer among females in the United States
The incidence of breast cancer in the United States is 2 or more times the rate observed in any of the fifteen Asian countries
Incidence Rates of Selected Cancers
Incidence Rates for Breast Cancer in Females by Country

Cambodia China India Indonesia Japan Korea Laos Malaysia Mongolia Philippines Singapore Sri Lanka Taiwan Thailand Vietnam United States 0 20 40 60 Rate per 100,000
Age-standardized to the World Standard Population. Source: Taiwan Cancer Registry Annual Report 2005 (Taiwan); GLOBOCAN 2002, IARC (all other countries).
80
100
120
Incidence Rates for Cancer of the Colon and Rectum by Gender and Country
Cambodia China India Indonesia Japan Korea Laos Malaysia Mongolia Philippines Singapore Sri Lanka Taiwan Thailand Vietnam United States 0 10 20 30 40 50 Males Females
Rate per 100,000

Incidence Rates for Cancer of the Esophagus by Gender and Country

Cambodia China India Indonesia Japan Korea Laos Malaysia Mongolia Philippines Singapore Sri Lanka Taiwan Thailand Vietnam United States 0 5 10 15 Rate per 100,000
Data unavailable for females, Taiwan. Age-standardized to the World Standard Population. Source: Taiwan Cancer Registry Annual Report 2005 (Taiwan); GLOBOCAN 2002, IARC (all other countries).
Males Females
20
25
30
Incidence Rates for Liver Cancer by Gender and Country

Cambodia China India Indonesia Japan Korea Laos Malaysia Mongolia Philippines Singapore Sri Lanka Taiwan Thailand Vietnam United States 0 10 20 30 40 50 60 70 80 90 100 Males Females
Rate per 100,000

Incidence Rates for Cancer of the Lung and Bronchus by Gender and Country
Cambodia China India Indonesia Japan Korea Laos Malaysia Mongolia Philippines Singapore Sri Lanka Taiwan Thailand Vietnam United States 0 10 20 30 40 50 60 70 Males Females
Rate per 100,000

Incidence Rates for Prostate Cancer in Males by Country

Cambodia China India Indonesia Japan Korea Laos Malaysia Mongolia Philippines Singapore Sri Lanka Taiwan Thailand Vietnam United States 0 20 40 60 80 100 120 140
Rate per 100,000

Incidence Rates for Stomach Cancer by Gender and Country

Cambodia China India Indonesia Japan Korea Laos Malaysia Mongolia Philippines Singapore Sri Lanka Taiwan Thailand Vietnam United States 0 10 20 30 40 50 60 70 Males Females
Rate per 100,000

Incidence Rates for Cancer of the Uterine Cervix in Females by Country

Cambodia China India Indonesia Japan Korea Laos Malaysia Mongolia Philippines Singapore Sri Lanka Taiwan Thailand Vietnam United States 0 5 10 15 20 25 30 35 40 45
Rate per 100,000

Distribution of Total New Cases of Cancer for Males Worldwide
US 13%
China 23%
Rest of World 46%
Total New Cancer Cases for Males = 5.8 Million per Year
Excludes non-melanoma skin cancer. Source: Taiwan Cancer Registry Annual Report 2005 (Taiwan); GLOBOCAN 2002, IARC (all other countries).
Percent of New Worldwide Cases of Cancer in Males by Country, for Each Site
Worldwide Number of New Cases of Cancer in Males (Thousands)
All Sites (5,801) Colon and Rectum (550) Esophagus (315) Liver (442) Lung (965) Prostate (679) Stomach (603)
2 2 .8
7 .0
1.4
5 .3
1.1
0 .8
0 .7
0 .7
0 .7
13 .1
4 5 .8
16 .0
3 .5
1.8
10 .5
1.0
0 .8
1.0
0 .5
0 .6
15 .5
4 8 .2
5 5 .1
9 .4
0 .1
3 .7
0 .6
0 .2
0 .4
0 .2
0 .3
3 .5
2 5 .8
5 6 .8
2 .1
2 .1
6 .2
2 .5
1.1
1.6
2 .3
1.6
2 .3
2 0 .9
2 7 .9
3 .7
1.6
4 .9
1.2
1.1
0 .7
0 .8
12 .3
4 4 .6
1.5
2 .5
0 .7
2 .5
0 .2
0 .5
0 .4
0 .2
0 .1
3 5 .3
5 5 .9
4 3 .8
3 .8
0 .4
12 .2
2 .6
0 .3
0 .4
0 .2
1.0
2 .3
3 2 .5
China
Male Population (Millions) (684.3)
India
(591.7)
Indonesia
(118.8)
Japan
(62.1)
Korea
(24.2)
Philippines
(48.1)
Taiwan
(11.6)
Thailand
(32.4)
Vietnam
(42.7)
US
(149.3)
Rest of World (1,623.2)
The 9 Asian countries represented are those contributing 1% or more of the worlds total new cancer cases or 1% or more of the specific cancer listed. The remaining 6 Asian countries not shown are also excluded from Rest of World. All sites excludes non-melanoma skin cancer. Source: Taiwan Cancer Registry Annual Report 2005 (Taiwan); GLOBOCAN 2002, IARC (all other countries).
Distribution of Total New Cases of Cancer for Females Worldwide
US 13%
China 17%
15 Asian Countries 37% Rest of World 50%
Total New Cancer Cases for Females = 5.1 Million per Year
Excludes non-melanoma skin cancer. Source: Taiwan Cancer Registry Annual Report 2005 (Taiwan); GLOBOCAN 2002, IARC (all other countries).
Percent of New Worldwide Cases of Cancer in Females by Country, for Each Site
Worldwide Number of New Cases of Cancer in Females (Thousands)
All Sites (5,060) Breast (1,151) Colon and Rectum (473) Esophagus (147) Liver (184) Lung (387) Stomach (331) Uterine Cervix (493)
17 .1
8 .8
2 .0
4 .2
0 .9
1.0
0 .6
0 .7
13 .2
5 0 .0
11.0
7 .2
2 .2
2 .8
0 .5
1.1
0 .6
0 .5
18 .2
5 4 .8
13 .2
2 .9
2 .0
8 .0
1.0
0 .8
0 .9
0 .4
17 .0
5 2 .7
5 4 .5
14 .2
0 .3
1.3
0 .2
0 .2
0 .2
2 .2
2 5 .9
5 1.6
2 .4
1.3
6 .8
1.8
0 .9
1.5
2 .7
2 .6
2 6 .9
3 2 .8
2 .1
1.6
4 .9
1.0
0 .9
0 .8
2 2 .2
3 2 .0
3 8 .9
3 .6
0 .6
10 .9
2 .3
0 .4
0 .4
0 .3
2 .4
3 8 .9
9 .3
2 6 .8
3 .1
1.6
1.0
1.2
0 .4
1.3
2 .7
5 0 .4
China
Female Population (Millions) (645.8)
India
(556.3)
Indonesia
(118.7)
Japan
(65.2)
Korea
(24.2)
Philippines
(48.0)
Taiwan
(11.3)
Thailand
(33.1)
US
(154.5)
Rest of World (1,684.4)
The 9 Asian countries represented are those contributing 1% or more of the worlds total new cancer cases or 1% or more of the specific cancer listed. The remaining 7 Asian countries not shown are also excluded from Rest of World. All sites excludes non-melanoma skin cancer. Source: Taiwan Cancer Registry Annual Report 2005 (Taiwan); GLOBOCAN 2002, IARC (all other countries).
Morbidity and Mortality: Mortality
Mortality Rates and Mortality-to-Incidence Ratios for Total Cancers by Gender and Country
MR:IR
Males, Females 0.77, 0.62 0.78, 0.67 0.74 , 0.65 0.77, 0.59 0.59, 0.49 0.63, 0.48 0.80, 0.65 0.78, 0.63 0.85, 0.78
Cambodia China India Indonesia Japan Korea Laos Malaysia Mongolia Philippines Singapore Sri Lanka Taiwan Thailand Vietnam United States 0 50 100 150 200
Males Females
0.79, 0.68
0.72, 0.55 0.70, 0.61 0.60, 0.44 0.81, 0.64 0.81, 0.65
0.38, 0.36
250
Rate per 100,000

Excludes non-melanoma skin cancer. Age-standardized to the World Standard Population. Mortality-to-incidence ratio (MR:IR): An age-standardized surrogate measure of survival obtained by dividing the mortality rate by the incidence rate. The higher the ratio, the lower the survival. Source: Taiwan Cancer Registry Annual Report 2005 (Taiwan); GLOBOCAN 2002, IARC (all other countries).
Mortality Rates of Selected Cancers
Mortality Rates and Mortality-to-Incidence Ratios for Breast Cancer in Females by Country
MR:IR
0.44 0.29 0.54 0.43 0.25
Cambodia China India Indonesia Japan Korea Laos Malaysia Mongolia Philippines Singapore Sri Lanka Taiwan Thailand Vietnam United States 0 5 10 15 Rate per 100,000 20 25 30
0.22
0.43 0.44 0.53 0.58 0.32 0.44 0.22 0.38 0.44 0.19
Age-standardized to the World Standard Population. Mortality-to-incidence ratio (MR:IR): An age-standardized surrogate measure of survival obtained by dividing the mortality rate by the incidence rate. The higher the ratio, the lower the survival. Source: Taiwan Cancer Registry Annual Report 2005 (Taiwan); GLOBOCAN 2002, IARC (all other countries).
Mortality Rates and Mortality-to-Incidence Ratios for Cancer of the Colon and Rectum by Gender and Country
MR:IR
Males, Females 0.61, 0.65
0.58, 0.58
0.72, 0.69 0.64, 0.63 0.35, 0.42 0.44, 0.42 0.64, 0.63 0.65, 0.65 1.14, 0.74 0.64, 0.65 0.56, 0.54 0.64, 0.62 0.43, 0.40 0.63, 0.63 0.64, 0.63 0.34, 0.35
Males Females
25
Rate per 100,000

Mortality Rates and Mortality-to-Incidence Ratios for Cancer of the Esophagus by Gender and Country
MR:IR
Cambodia China India Indonesia Japan Korea Laos Malaysia Mongolia Philippines Singapore Sri Lanka Taiwan Thailand Vietnam United States 0 5 10 15 Rate per 100,000 20
0.79, 0.80
0.87, 0.86 1.00, 1.00 0.75, 0.85 0.76, 0.56 0.88, 0.80 0.91, 0.90 0.72, 0.82 0.92, 0.92 0.77, 1.36 0.91, 0.92 0.85, n/a 0.88, 0.90 0.92, 1.00 0.86, 0.92
Males Females
25
30
Data unavailable for females, Taiwan. Age-standardized to the World Standard Population. Mortality-to-incidence ratio (MR:IR): An age-standardized surrogate measure of survival obtained by dividing the mortality rate by the incidence rate. The higher the ratio, the lower the survival. Source: Taiwan Cancer Registry Annual Report 2005 (Taiwan); GLOBOCAN 2002, IARC (all other countries). 2008 Pfizer Inc. All rights reserved.
Mortality Rates and Mortality-to-Incidence Ratios for Liver Cancer by Gender and Country
MR:IR
0.93, 0.94
0.96, 0.91 0.94, 0.92 0.91, 0.88 0.76, 0.75 0.95, 0.95 0.95, 0.94 0.94, 0.83 0.88, 0.88 1.01, 1.25 0.91, 1.00 0.71, 0.67 0.97, 0.97 0.94, 0.95 0.80, 1.00
Males Females
100
Rate per 100,000

Mortality Rates and Mortality-to-Incidence Ratios for Cancer of the Lung and Bronchus by Gender and Country
MR:IR
0.87, 0.86
0.88, 0.89 0.93, 0.93 0.85, 0.78 0.81, 0.80 0.92, 0.92 0.93, 0.93 0.87, 1.15 0.93, 0.93 0.96, 0.98 0.92, 0.88 0.90, 0.80 0.95, 0.95 0.93, 0.93 0.79, 0.74
Males Females
50
Rate per 100,000

Mortality Rates and Mortality-to-Incidence Ratios for Prostate Cancer in Males by Country
MR:IR
0.61 0.63 0.65 0.63 0.45
Cambodia China India Indonesia Japan Korea Laos Malaysia Mongolia Philippines Singapore Sri Lanka Taiwan Thailand Vietnam United States 0 2 4 6 8 10 12 14 16 18
0.37
0.63 0.63 0.46 0.72 0.39 0.63 0.33 0.64 0.61 0.13
Rate per 100,000

Mortality Rates and Mortality-to-Incidence Ratios for Stomach Cancer by Gender and Country
MR:IR
0.79, 0.79
0.86, 0.86 0.86, 0.86 0.46, 0.49 0.53, 0.56 0.84, 0.84 0.86, 0.85 0.85, 0.83 0.91, 0.90 0.80, 0.77 0.83, 0.89 0.72, 0.62 0.88, 0.86 0.85, 0.85 0.56, 0.67
Males Females
50
Rate per 100,000

Mortality Rates and Mortality-to-Incidence Ratios for Cancer of the Uterine Cervix in Females by Country
MR:IR
0.56 0.56 0.58 0.52 0.35
Cambodia China India Indonesia Japan Korea Laos Malaysia Mongolia Philippines Singapore Sri Lanka Taiwan Thailand Vietnam United States 0 5 10 15 20 25
0.26
0.52 0.54 0.56 0.75 0.64 0.55 0.44 0.42 0.55 0.30
Rate per 100,000

Morbidity and Mortality: Prevalence
Prevalence
In fourteen of the fifteen Asian countries (prevalence data unavailable for Taiwan), there are 3.6 million males and 4.0 million females living with cancer and diagnosed within the past 5 years (5-year partial prevalence) The magnitude of the surviving population is a function of incidence rates new cases diagnosed during the year as well as associated mortality rates
Number of Males Living with Cancer and Diagnosed Within the Past 5 Years, by Country
Cancer Site
Colon and Rectum Esophagus Larynx Liver Lung and Bronchus Melanoma of the Skin Nasopharynx Non-Hodgkin Lymphoma Oral Cavity Other Pharynx Prostate Stomach Urinary Bladder All Sites (Excluding NonMelanoma Skin) 584 365,092 683 628 127,573 70,384 42,521 12,634 62,725 244,444 19,691 5,377 140 1,472 1,300 90 404 8,887 700 585 3,283 7,910 187,455 12,787 10,724 141 3,294 5,440 1,173 1,036,628 2,860 2,707 3,928 852 5,241 480 114,156 222,196 11,833
Cambodia China India Indonesia Japan Korea Laos Malaysia Mongolia Philippines Singapore Sri Lanka Thailand Vietnam United States
890
200,230 147,435
46,643
23,713
218,939
13,011
287
3,593 129
9,990
1,748
1,170
6,488
8,454
288,503
59,347 60,805 89,071 5,405 8,498 162 224 1,698 326 155 8,336 734
1,528 4,984 752 4,875 3,444 6,285 151,343 132,335
7,813
1,577,755
723,222
133,183
887,507
82,965
2,676
20,535
1,761
68,639
7,663
17,574
53,812
59,885
2,431,746
Rank:
1st
2nd
3rd
4th
5th
Data unavailable for Taiwan. Source: GLOBOCAN 2002, IARC.

Number of Females Living with Cancer and Diagnosed Within the Past 5 Years, by Country
Cancer Site
Breast Colon and Rectum Esophagus Liver Lung and Bronchus Melanoma of the Skin Oral Cavity Ovary Stomach Thyroid Uterine Cervix Uterine Corpus All Sites (Excluding Nonmelanoma Skin 14,154 1,542,192 1,089,125 511 5,484 142,616 370,243 46,849 17,587 267,323 663,553 83,169 4,300 28,716 471 186,785 77,170 53,627 20,893 109,677 9,626 5,928 13,920 289 1,012 4,696 1,532 32,183 2,134 123,874 553 235 315 2,171 264 8,996 18,970 1,009 812 11,622 24,021 82,866 78,811 1,763 4,649 4,433 19,846 19,262 207,913 2,312,952 8,735 708 2,033 2,028 4,665 3,866 4,295 104,455 41,181
3,697 599
426,057 151,250
269,470 33,015
90,611 23,216
146,847 139,292
17,941 10,467
787
10,697 3,081
230
44,001 8,778
4,329 1,674
7,807
19,096 5,147
19,049 6,390
968,731 270,698
116 199 130,683 106,636
Rank:
1st
2nd
3rd
4th
5th
Data unavailable for Taiwan. Source: GLOBOCAN 2002, IARC.

Country Data Tables
Cambodia
2008 Population (Millions)
Total Males Females 14.2 7.0 7.3
Source: US Census Bureau, International Data Base 2008. Male and female populations may not add to total due to rounding.
Incidence, Prevalence, Mortality, and Mortality-to-Incidence Ratios for Common Cancers in Males and Females
Incidence Cancer Site
Age-Standardized Rate per 100,000 Number of New Cases of Cancer
5-Year Prevalence
Rate per 100,000 (not agestandardized) Number of Persons Living with Cancer
Mortality
Age-Standardized Rate per 100,000
Mortality-toIncidence Ratio MR:IR 0.93 0.85
Lung and Bronchus
22.5 16.1
588 432
7.7 9.4
480 584
20.9 13.7
Males
Stomach
Liver
Colon and Rectum Oral Cavity
15.0
11.3 10.2
478
358 260
3.9
14.3 10.1
244
890 628
14.2
6.9 5.4
0.95
0.61 0.53
Uterine Cervix
38.7
21.5 5.4 5.1 4.9
1,768
1,032 239 215 203
83.0
55.7 9.1 4.4 2.6
5,484
3,679 599 294 170
21.6
9.5 3.5 4.3 4.5
0.56
0.44 0.65 0.84 0.92
Females
Breast Colon and Rectum Stomach Lung and Bronchus
Age-standardized to the World Standard Population. Source: GLOBOCAN 2002, IARC. US Census Bureau International Data Base country population for 2002 used as weights for prevalence rates.
China
Total Males Females 1,330 684 646
5-Year Prevalence
Rate per 100,000 (not agestandardized)
Number of Persons Living with Cancer
Mortality
Mortality-toIncidence Ratio MR:IR 0.87 0.79 0.93 0.79 0.58 0.79 0.86 0.29 0.94
Lung and Bronchus
42.4 41.4 37.9 27.4 13.6 19.2 19.0 18.7 14.2
269,650 264,460 250,907 173,802 88,142 128,478 126,718 126,227 94,937
33.6 55.2 17.3 22.3 30.3 30.0 16.8 68.4 7.0
222,196 365,092 114,156 147,435 200,230 186,785 104,455 426,057 43,776
36.7 32.7 35.3 21.6 7.9 15.1 16.3 5.5 13.3
Males Females
Stomach Liver Esophagus Colon and Rectum Stomach Lung and Bronchus Breast Liver
Esophagus
12.0
79,950
10.8
66,950
9.6
0.80
India
Total Males Females 1,148 592 556
5-Year Prevalence
Mortality
Mortality-toIncidence Ratio MR:IR 0.56 0.76
Oral Cavity
12.8 9.6
52,008 38,542
23.8 13.1
127,573 70,384
7.2 7.3
Males
Other Pharynx
Lung and Bronchus

Esophagus Larynx Uterine Cervix
9.0
7.6 6.2 30.7 19.1 7.5 5.1 4.9
35,495
29,652 24,216 132,082 82,951 30,906 20,805 21,146
5.1
4.8 11.1 73.6 53.5 15.3 3.5 10.7
27,477
25,555 59,347 370,243 269,470 77,170 17,442 53,627
7.9
6.6 4.2 17.8 10.4 4.2 4.4 3.8
0.88
0.87 0.68 0.58 0.54 0.56 0.86 0.78
Females
Breast Oral Cavity Esophagus Ovary
Indonesia
Total Males Females 238 119 119
5-Year Prevalence
Mortality
Mortality-toIncidence Ratio MR:IR 0.93 0.64 0.94 0.63 0.70
Lung and Bronchus
20.0 11.9 11.3 7.0 6.0
15,432 9,678 9,155 5,074 5,313
10.8 21.6 4.1 11.5 9.8
11,833 23,713 4,490 12,634 10,724
18.6 7.6 10.6 4.4 4.2
Males
Colon and Rectum Liver Prostate
Non-Hodgkin Lymphoma
Breast
26.1
15.7 10.6 8.1
25,208
15,050 9,577 7,910
82.3
42.6 21.1 19.0
90,611
46,849 23,216 20,893
11.3
8.1 6.7 4.7
0.43
0.52 0.63 0.58
Females
Uterine Cervix Colon and Rectum Ovary
Lung and Bronchus
6.8
6,227
4.7
5,167
6.3
0.93
Japan
5-Year Prevalence
Mortality
Mortality-toIncidence Ratio MR:IR 0.46 0.35 0.85 0.91 0.45
Stomach
62.1 49.3 38.1 23.1 12.6
73,785 57,764 47,564 27,271 16,808
393.1 352.1 143.2 97.8 100.9
244,444 218,939 89,071 60,805 62,725
28.7 17.3 32.4 21.0 5.7
Males
Colon and Rectum Lung and Bronchus Liver Prostate
Breast
32.7
26.5 26.1 12.3 8.0
32,245
37,887 35,994 18,889 7,772
225.9
214.3 168.7 63.3 44.2
146,847
139,292 109,677 41,181 28,716
8.3
11.1 12.7 9.6 2.8
0.25
0.42 0.49 0.78 0.35
Females
Colon and Rectum Stomach Lung and Bronchus Uterine Cervix
Korea
5-Year Prevalence
Mortality
Mortality-toIncidence Ratio MR:IR 0.53
Stomach
69.6
15,912
82.8
19,691
37.1
Males
Lung and Bronchus

Liver Colon and Rectum Esophagus Stomach
53.3
47.1 24.7 8.9 26.8 20.4 17.9
11,722
11,169 5,650 1,985 7,737 5,511 4,949
35.7
22.7 54.7 6.6 40.7 75.9 58.9
8,498
5,405 13,011 1,572 9,626 17,941 13,920
43.0
35.9 10.9 6.8 15.0 4.4 4.7
0.81
0.76 0.44 0.76 0.56 0.22 0.26
Females
Breast Uterine Cervix
Colon and Rectum

Lung and Bronchus
15.8
12.8
4,561
3,768
44.3
11.8
10,467
2,780
6.7
10.3
0.42
0.80
Laos
5-Year Prevalence
Mortality
Mortality-toIncidence Ratio MR:IR 0.95 0.92 0.64 0.85 0.72 0.52 0.43 0.95 0.92 0.53
Liver
22.4 18.3 7.4 4.1 3.6 16.8 10.9 7.5 6.5 6.0
340 268 114 100 71 317 217 125 110 96
5.7 7.8 10.0 3.7 4.9 34.7 27.0 2.0 3.2 8.1
162 224 287 105 141 1,012 787 58 92 235
21.2 16.9 4.7 3.5 2.6 8.8 4.7 7.1 6.0 3.2
Males Females
Lung and Bronchus Colon and Rectum Leukemia
Non-Hodgkin Lymphoma
Uterine Cervix Breast Liver Lung and Bronchus Oral Cavity
Malaysia
Source: US Census Bureau, International Data Base 2008. Male and female populations may not add to total due to rounding.
5-Year Prevalence
Mortality
Mortality-toIncidence Ratio (MR:IR) 0.93 0.65 0.86 0.64 0.95
Lung and Bronchus
30.0 19.3 13.2 11.4 11.0
2,262 1,509 1,007 1,090 888
14.9 31.5 11.4 23.7 3.8
1,698 3,593 1,300 2,707 432
27.9 12.5 11.4 7.3 10.4
Males
Colon and Rectum Stomach Nasopharynx Liver
Breast
30.8
15.7 15.6 10.9 8.4
2,974
1,492 1,329 914 813
94.9
41.7 27.3 6.4 19.3
10,697
4,696 3,081 725 2,171
13.5
8.4 10.1 10.1 5.0
0.44
0.54 0.65 0.93 0.60
Females
Uterine Cervix Colon and Rectum Lung and Bronchus Ovary
Mongolia
5-Year Prevalence
Mortality
Mortality-toIncidence Ratio MR:IR
Liver
98.9
39.2 31.8 24.5 4.4 57.3 23.3 19.6 18.0 11.3
687
290 209 161 32 442 194 150 171 89
23.8
29.4 11.3 9.4 5.8 14.5 19.2 8.5 40.3 4.8
326
404 155 129 79 199 264 116 553 66
93.4
33.4 27.6 17.6 5.0 47.3 19.4 16.1 10.1 13.0
0.94
0.85 0.87 0.72 1.14 0.83 0.83 0.82 0.56 1.15
Males Females
Stomach Lung and Bronchus Esophagus Colon and Rectum Liver Stomach Esophagus Uterine Cervix Lung and Bronchus
Philippines
5-Year Prevalence
Mortality
Lung and Bronchus
50.2 20.3 18.8 18.6 8.9 46.6 20.9 14.7 13.5 11.5
10,823 4,851 4,198 3,552 1,944 13,051 6,000 3,723 3,358 3,352
19.6 5.7 23.5 20.9 5.9 103.5 44.6 20.6 6.2 20.5
8,336 2,402 9,990 8,887 2,523 44,001 18,970 8,778 2,626 8,735
46.6 17.9 12.1 13.3 8.1 27.1 15.6 9.5 12.6 6.3
Males Females
Liver Colon and Rectum Prostate Stomach Breast Uterine Cervix Colon and Rectum Lung and Bronchus Ovary
Singapore
5-Year Prevalence
Mortality
Lung and Bronchus
46.4 35.1 22.3 18.4 14.6 48.7 29.9 18.3 13.2 11.1
1,001 772 478 403 349 1,213 733 448 323 273
35.6 84.8 28.4 9.1 41.4 202.5 78.3 15.6 47.2 33.1
734 1,748 585 188 852 4,329 1,674 334 1,009 708
44.6 19.6 17.8 18.6 8.4 15.8 16.2 17.9 8.4 4.6
Males Females
Colon and Rectum Stomach Liver Nasopharynx Breast Colon and Rectum Lung and Bronchus Uterine Cervix Ovary
Sri Lanka
5-Year Prevalence
Mortality
Mortality-toIncidence Ratio MR:IR 0.54 0.92 0.91
Oral Cavity
24.5 9.9 8.9
2,284 935 828
55.3 7.7 7.0
5,440 752 687
13.2 9.1 8.1
Males
Long and Bronchus Esophagus
Other Pharynx Larynx

Breast
6.9 6.8
23.6 17.2 11.8 9.2 9.0
645 637
2,180 1,544 1,035 817 810
11.9 15.5
77.8 46.3 9.0 20.2 20.2
1,173 1,528
7,807 4,649 899 2,033 2,028
5.3 4.1
10.3 9.5 10.8 5.1 5.6
0.77 0.60
0.44 0.55 0.92 0.55 0.62
Females
Uterine Cervix Esophagus Oral Cavity Ovary
Taiwan
5-Year Prevalence
Mortality
Mortality-toIncidence Ratio MR:IR 0.71 0.43 0.90 0.33 0.72 0.22 0.40 0.67
Liver
56.1 41.8 41.4 19.7 16.8 49.2 30.9 21.2
7,159 5,497 5,566 2,704 2,288 6,594 4,107 2,757
39.9 18.0 37.4 6.5 12.1 10.8 12.5 14.2
Males Females
Colon and Rectum Long and Bronchus Prostate Stomach Breast Colon and Rectum Liver
Long and Bronchus

Uterine Cervix
20.6
14.7
2,746
1,977
16.5
6.5
0.80
0.44
Prevalence data unavailable for Taiwan. Age-standardized to the World Standard Population. Source: Taiwan Cancer Registry Annual Report 2005. US Census Bureau International Data Base country population for 2002 used as weights for prevalence rates.
Thailand
5-Year Prevalence
Mortality
Liver
38.6 25.5 10.7 4.8 4.7 19.8 17.2 16.6 10.4 7.1
10,195 6,429 2,744 1,195 1,336 6,243 4,995 5,282 3,026 2,108
16.0 15.7 20.9 10.6 8.6 62.6 7.5 60.2 7.6 16.2
4,984 4,875 6,488 3,283 2,681 19,846 2,390 19,096 2,412 5,147
37.3 24.1 6.7 2.6 3.1 8.4 16.6 6.3 9.9 4.5
Males Females
Long and Bronchus Colon and Rectum Urinary bladder Non-Hodgkin Lymphoma Uterine Cervix Liver Breast Lung and Bronchus Colon and Rectum
Vietnam
5-Year Prevalence
Mortality
Mortality-toIncidence Ratio MR:IR 0.93 0.94 0.85
Lung and Bronchus
29.6 23.7 21.8
8,089 6,933 6,104
15.7 8.6 19.8
6,285 3,444 7,910
27.4 22.3 18.6
Males
Liver Stomach
Colon and Rectum

Nasopharynx Uterine Cervix
11.8
6.9 20.2 16.2 9.9 8.3 7.2
3,428
2,113 6,224 5,268 3,159 2,601 2,219
21.1
13.1 47.1 46.6 10.5 15.6 4.3
8,454
5,241 19,262 19,049 4,295 6,390 1,775
7.6
4.5 11.2 7.1 8.4 5.2 6.7
0.64
0.65 0.55 0.44 0.85 0.63 0.93
Females
Breast Stomach Colon and Rectum Long and Bronchus
Preventable Risk Factors
Prevalence of Current Smoking Among Adults Aged 15 Years and Older by Country and Gender
70 60
Percent of Population
50 40 30 20 10 0
Cambodia China India Indonesia Japan Korea Laos Malaysia Mongolia Philippines Sri Lanka Thailand Vietnam United States
Total
Men
Women
Data unavailable for Singapore, Taiwan. Source: WHOSIS 2005.

Average Annual Alcohol Consumption per Capita in Liters Among Adults Aged 15 Years and Older by Country
Average Annual Alcohol Consumption per Capita (Liters)
10 9 8 7 6 5 4 3 2 1 0
Data unavailable for Taiwan. Source: WHOSIS 2003.

Appendix
Definitions
Alcohol consumption: Liters of pure alcohol per capita, computed as the sum of alcohol production and imports, less alcohol exports, divided by the adult population (aged 15 years and older). Current smoking: Current tobacco smoking includes both daily and non-daily or occasional smoking of cigarettes, cigars, pipes, or any other smoked tobacco products.
Other Definitions Disease or Condition Rates

Age-standardized rates: Rates adjusted for differences in the age distribution between the population of interest and a standard population. The standard population used in this report is the WHO World Standard Population. For additional information: http://www.who.int/infobase/help.aspx?helpid=293 Incidence: The number of new cases of a disease in a given time period among the population at risk of the disease.
Prevalence: The number of persons diagnosed with a disease. It is a function of incidence and mortality. Five-year prevalence is the number of persons alive 5 years after a diagnosis of cancer.
Mortality: The number of deaths occurring in a given period in a specified population. It can be expressed as an absolute number of deaths per year or as a rate per 100,000 persons per year. Mortality-to-incidence rate ratio: As an indirect measure of cancer survival, a mortality-to incidence rate ratio (MR:IR) was calculated by dividing the mortality rate by the incidence rate; the higher the ratio, the lower the survival. Mortality to incidence rate ratios greater than 1.0 can occur for rare cancers due to statistical fluctuations. For example, within the reference period all who contracted the cancer die, plus some who contracted it prior to the reference period also die in the reference period.
International Classification of Diseases for Oncology, 3rd Edition (ICD-0-3), ICD-9th and ICD-10th Revision Codes
Cancer Site
Breast Brain and nervous system Colon and rectum Corpus uteri Esophagus Hodgkins Disease Kidney and other and Unspecified urinary organs Larynx Leukemia Liver and intrahepatic bile ducts Lung, trachea, and bronchus Melanoma of the skin Multiple myeloma Nasopharynx Non-Hodgkins lymphomas Oral cavity Other pharynx Ovary and other uterine adnexa Pancreas Prostate Stomach Testis Thyroid Urinary bladder Uterine cervix All Sites (excluding non-melanoma skin)
ICD-10
C50 C70C72 C18C21 C54 C15 C81 (M965M966) C64C66, C68 C32 C91C95 C22 C33, C34 C43 C90 (M973, M976) C11 C82C83, C96 (M959, M967M972, M974) C00C08 C14 C56, C57.04 C25 C61 C16 C62 C73 C67 C53 C00C96, but C44 (M800M998)
ICD-9
174175 191192 153154 182 150 201 189 161 204208 155 162 172 203 147 200, 202 140145 149 183 157 185 151 186 193 188 180 140208
Breast cancer analyzed in females only. ICD-0-3 codes used for incidence in the Taiwan 2005 registry report. ICD-0-3 uses the ICD-10 classification for malignant neoplasms, except for those categories which relate to morphological types of tumors; here M codes are used. ICD-9 codes used for mortality for Taiwan. ICD-9 code 202 is not 2008 Pfizer Inc. All rights reserved. included in Non-Hodgkin lymphoma mortality for Taiwan. ICD-10 codes used for incidence and mortality for all other countries.
Human Development Index (HDI) for South and East Asia

Countries With More Than One Million Population
Country High Human Development
Japan Taiwan 8 23 0.953 0.932
World Rank
HDI Value (2005)
Singapore
South Korea Malaysia
25
26 63 78 81 90 99 105 107 114 128 130 131 132
0.922
0.921 0.811 0.781 0.777 0.771 0.743 0.733 0.728 0.700 0.619 0.601 0.598 0.583
Medium Human Development

Thailand China Philippines Sri Lanka Viet Nam Indonesia Mongolia India Laos Cambodia Myanmar
Pakistan
Bangladesh Nepal Papua New Guinea Timor-Leste
136
140 142 145 150
0.551
0.547 0.534 0.530 0.514
Without HDI Rank

Afghanistan Korea (Democratic People's Rep. of)
Source: Directorate General of Budget, Accounting and Statistics, Executive Yan, Republic of China, 2006. (Taiwan). United Nations Development Programme. Human Development Report 2007/2008. http://hdr.undp.org/en/statistics/data/. November 2008. (all other countries).
South and East Asian Countries with Less Than One Million Population
Country
Bhutan Brunei Fiji Kiribati Maldives Marshall Islands Micronesia (Federated States of) Nauru Palau Samoa Solomon Islands Tonga Tuvalu
Population
682,321 381,371 932,000 110,356 385,925 63,174 107,665 13,770 21,093 217,083 581,318 119,009 12,177
Vanuatu
215,446
Source: US Census Bureau. International Data Base 2008. http://www.census.gov/ipc/www/idb/summaries.html. November 2008.
Medical Division
PG283663SK
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All rights reserved
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Burden of Cancer in Asia

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Burden of Cancer in Asia

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The Burden of Cancer in Asia

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Distribution of Worldwide Population

Rest of World 47%

15 Asian Countries 48%

India 17% 13 Asian Countries 11%

Total Population = 6.7 Billion

Source: US Census Bureau, International Data Base 2008.

Distribution of Worldwide Male Population

Rest of World 47%

15 Asian Countries 49%

India 18% 13 Asian Countries 11%

Total Population = 3.38 Billion

Source: US Census Bureau, International Data Base 2008.

Distribution of Worldwide Female Population

Rest of World 48%

15 Asian Countries 48%

India 17% 13 Asian Countries 11%

Total Population = 3.33 Billion

Demographic Characteristics by Country

Median Age (Years)

Proportion 65 Years and Older (%)

Source: US Census Bureau, International Data Base 2008.

Morbidity and Mortality: Incidence

2008 Pfizer Inc. All rights reserved.

United States Mongolia

South Korea South Korea

Nepal Taiwan Burma Laos Vietnam Philippines

2008 Pfizer Inc. All rights reserved.

United States Mongolia

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Incidence Rates for Total Cancers by Gender and Country

Rate per 100,000

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Incidence Rates of Selected Cancers

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Incidence Rates for Breast Cancer in Females by Country

Rate per 100,000

Incidence Rates for Cancer of the Esophagus by Gender and Country

Incidence Rates for Liver Cancer by Gender and Country

Rate per 100,000

Rate per 100,000

Incidence Rates for Prostate Cancer in Males by Country

Rate per 100,000

Incidence Rates for Stomach Cancer by Gender and Country

Rate per 100,000

Incidence Rates for Cancer of the Uterine Cervix in Females by Country

Rate per 100,000

Distribution of Total New Cases of Cancer for Males Worldwide

Rest of World 46%

15 Asian Countries 41%

India 7% 13 Asian Countries 11%

Rest of World (1,623.2)

Distribution of Total New Cases of Cancer for Females Worldwide

15 Asian Countries 37% Rest of World 50%

India 9% 13 Asian Countries 11%

Rest of World (1,684.4)

Morbidity and Mortality: Mortality

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Rate per 100,000

Mortality Rates of Selected Cancers