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Pharma Grade Resins

Range of speciality resins for applications in pharmaceutical formulations Highly purified to minimise heavy metals and organic extractables Completely non-toxic as confirmed by their high LD50 values Manufactured in state-of-the-art facility

ISO 9001 & 14001 certified, FDA approved manufacturing facility,All India Service Network & also exported widely.

Pharma Grade Resins

Applications
Taste masking of bitter drugs Sustained release Vit. B12 stabilisation

INDION Resins
204/214/234/254/294/ 464
224/244/254/284

Tablet disintegration
Drug actives

264
234/294/414 254/454/404

Taste Masking of Bitter Drugs


Taste masking of bitter drugs containing amino groups Principles
drug forms complex (Resinate) with ion exchange resin The complex does not break at average pH of 6.7 of saliva Quantitative elution of drug at low pH in the stomach

Taste Masking of Bitter Drugs


Reaction Complex Formation
R-COOH + D-NH2 R-COO-NH3-D Resin Drug Complex (in amine form) (Resinate)
R-COOK + D-NH2 HCL Resin Drug (in HCl form) R-COO-NH3-D + KCL Complex (Resinate)

Taste Masking of Bitter Drugs


Reactions Drug Release
R-COO-NH3-D + HCl Complex R-COOH + DNH2HCl Resin Drug

Taste Masking of Bitter Drugs


Chloroquine Phosphate Ciprofloxacin Hydrochloride Norfloxacin / Ofloxacin Dexomethorphane Hydrobromide Roxythromycin

Dicycloamine Hydrochloride
Quinine Sulphate

Famotidine

Valued Customers (Partial list)


Aristo Pharmaceuticals Alkem Laboratories Alembic Ltd. Bayer India Ltd Blue Cross Laboratories Cadila Pharmaceuticals Cipla Ltd Solvay E. Merck Emcure Pharmaceuticals

Valued Customers (Partial List)


F.D.C Ltd German Remedies IPCA Laboratories Indoco Remedies J.B.Chemicals / Lekar Pharma Relax Pharmaceuticals Nicholas Piramal Pfizer Ltd Ranbaxy Laboratories Sun Pharmaceuticals Medreich Sterilab Macleods Pharmaceuticals

Taste Masking
Indion - 204 Norfloxacin Ofloxacin Roxithromycin Dicyclomine Hydrochloride Nalidixic acid

Taste Masking
Indion - 234

Chloroquin Phosphate Chloroquin Sulphate Ciprofloxacin HCl Quinine Sulphate Lebaxacin HCl Metchlopramide HCl Amodiquine Sulphate Famotidine Dioctyl Sodium Succinate

Taste Masking
Indion 214 Indion 464 Indion - 254 Azithromycin Nicotine Bromohexine HCl Dextromethropan HBr Limoxycin HCl Pseudoephedrine HCl Ambroxol HCl Salbutamol Sulphate

PRODUCT EQUIVALENT CHART


ION EXCHANGE (I) LTD,.
INDION - 464 INDION - 254 (Sodium Polystyrene Sulphonate , USP/NF) INDION 294 (Polacrilin Potassium , USP/NF) INDION - 454 (Cholestyramine , USP)

ROHM & HAAS


. AMBERLITE - IRP 64 . AMBERLITE - IRP 69 . AMBERLITE - IRP 88 . DUOLITE - AP 143

LIST of APPLICATION DETAILS :


TM of Norfloxaci with INDION 204 TM of Ciprofloxacin with INDION 234 TM of Roxithromycin with INDION 204 TM of Chloroquin Phosphate with IND-234 TM of Diphenylamine HCl with IND-234D TM of Ofloxacin with INDION 204 TM of Azithromycin with INDION-214 TM of Dicyclomie HCl with INDION 204 TM of Ambroxol HCl with INDION 254

NEW APPLICATIONS :
Treatment of Hyperkaliemia using INDION 404. Treatment Hypercholesterolemia using INDION 454. Taste masking of Nicotine Polacrylex Using INDION-464 Purification of Aerosols and Biotechnology application by using PA-500 & PA-800. TM of Cefuroxime Axetil with INDION 214 TM of Cefpodoxim Proxetil with INDION-204

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