TEXTUS EPITHELIUM

PRESENTED FOR BSHB BLOCK TA. 2011/2012

KOMPETENSI
1. Mampu menjelaskan definisi textus epitelium 2. Mampu menyebutkan fungsi textus epitelium 3. Mampu menyebutkan macam-macam textus epithelium. 4. Mampu menjelaskan bagian-bagian textus epitelium.

TEXTUS EPITHELIUM ????

Jaringan avaskuler, tersusun atas beberapa sel
permukaan luar tubuh permukaan dalam rongga tubuh
Rongga tubuh yg berhubungan dgn permukaan luar tubuh seperti saluran pernafasan, saluran genitourinari

KLASIFIKASI JARINGAN EPITEL

1. Berdasarkan jumlah lapisan sel a. Selapis SIMPLE atau SIMPLEX b. Berlapis STRATIFIED atau STRATIFICATUM 2. Berdasarkan bentuknya SQUAMOUS SQUAMOSUM PIPIH CUBOIDAL CUBOIDEUM KUBUS COLUMNAR COLUMNARE SILINDRIS

TEXTUS EPITHELIUM SIMPLEX

TEXTUS EPITHELIUM STRATIFICATUM

TEXTUS EPITHELIUM KHUSUS

1. TEXTUS EPITHELIUM PSEUDOSTRATIFICATUM

TEXTUS EPITHELIUM KHUSUS

2. TEXTUS EPITHELIUM TRANSITIONAL

Spesific names are given to epithelium in certain locations : 1. Endothelium is epithelial lining of the blood and lymphatic vessels 2. Endocardium is the epithelial lining of ventricles and atria of the heart 3. Mesothelium is the epithelium that lines the walls and covers the contents of the closed cavities of the body (i.e. abdominal, pericardial and pleural cavities)

KARAKTERISTIK DASAR SEL-SEL PENYUSUN JARINGAN PITEL

A.Cell Junctions B.Free surface / apical domain, lateral domain and basal domain C.Basement membrane

POLARITAS SEL
Epithelial cells exhibit distinct polarity. They have an apical domain, a lateral domain, and a basal domain. Spesific biochemical characteristics are associated with each cell surface These characteristics and the geometric arrangements of the cells in the epithelium determine the functional polarity of all 3 cell domains.

MODIFIKASI DOMAIN APIKAL

1. Microvilli, cytoplasmic processes that extend from the cell surface 2. Steroecilia (stereovilli), microvilli of unusual length 3. Cilia, motile cytoplasmic processes

IKATAN ANTAR SEL PADA LATERAL DOMAIN:

1. Occluding Junctions zonula occludens (occludin,claudins,JAM) 2. Anchoring junctions zonula adherens - macula adherens / desmosome 3. Communicating junctions / gap junctions / nexuses

BASAL DOMAIN, IKATAN ANTARA SEL DGN MATRIKS EKSTRASELULER

1. Basement membrane 2. Cell to extracellular matrix junctions : Anchoring junctions : Focal adhesions & Hemidesmosomes 3. Basal cell membrane infoldings

KOMPONEN DOMAIN BASAL, SPESIALISASI PADA IKATAN SELMATRIKS EKSTRA SELULER

1. Basement membrane 2. Cell to extracellular matrix junctions : Anchoring junctions : Focal adhesions & Hemidesmosomes 3. Basal cell membrane infoldings

FUNGSI TEXTUS EPITELIUM

TRANSPORT ANTAR SEL
ABSORBSI

PROTEKSI

SEKRESI

FUNGSI

RESEPTOR

1. FUNGSI SEKRETORI
Berperan dlm proses sekresi produk-produk kelenjar. Bagian sekresi darisuatukelenjar dan duktusnya tersusun atas jar. Epitel.

2. FUNGSI ABSORBSI
Berperan dlm proses absorbbsi. Ditemukan pd Epitel columnare pd usus halus

3. FUNGSI TRANSPORT
a. transport material intersel melalui silia. b. Transport material dari jaringan epitelium ke jaringan ikat (atau sebaliknya)

4. FUNGSI PROTEKSI
Sebagai pelindung Seperti pada textus epitheliasis squamous stratificatum di epidermis.

5. FUNGSI RESEPTOR
Berperan dlm proses penerimaan dan penghantar rangsang eksternal. Seperti pada indera perasa pada lidah, penghidu pada mukosa nasal, retina pada mata,

Histogenesis of epithelium
The three germ layers in the developing embryo contribute to the formation of the various epithelia 1. Ectodermal derivatives 2. Mesodermal derivatives 3. Endodermal derivatives

Ectodermal derivatives
Surface ectoderm - epidermis - cornea & lens epithelia of the eye - enamel organ & enamel of the teeth - components of the inner ear - anterior lobe of pituitary gland adenohypophysis

Neuroectoderm - neural tube &its derivatives (CNS, sensoryEpt, etc) - neural crest &its derivatives

Mesodermal derivatives
Epithelium of the kidney and the gonads Mesothelium Endothelium Adrenal cortex Genital duct epithelium

ENDODERMAL DERIVATIVES
Respiratory

system epithelium Alimentary canal epithelium Extramural digestive gland epithelium Thyroid, parathyroid and thymus gland epithelial components Lining epithelium of the tympanic cavity and auditory (eustachian) tubes

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