AYAM ARAMBHA SHUBHAYA BHAVATHU

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NUTRITION AND MANAGEMENT OF DEGENERATIVE DISEASES.

03 Jul 2010

What is Nutrition?
Nutrition

is the relationship of food to the well being of the human body.

What is Nutrition? Contd.

It includes

the metabolism of foods, the nutritive value of foods, the qualitative and quantitative requirements for food at different ages and developmental levels to meet physiological changes and activity needs, the changes in nutrient and food requirements that accompany or assist in the reduced risks of degenerative conditions, and the economic, psychological, social and cultural factors that affect the selection and eating of foods.

What Does Nutrition Do?

All

living things need food and water to live. Eating a well-balanced diet while getting plenty of physical activity, maintaining a healthy weight, avoid smoking and controlling diseases such as heart disease and diabetes is the best approach to a healthy lifestyle.

You are what you eat?

It

is true that human body is really built from the nutrients it gets from food: water, protein, fat, carbohydrates, vitamins and minerals. On average: 60% of body weight is water, 20% is fat, and 20% is a combination of mostly protein plus carbohydrates, minerals and vitamins.

Food Pyramid

Nutrition needs
Each older adult has unique needs: so dietary recommendations should be individualized. ENERGY: Energy requirements decrease with age. Average caloric intake is 2000 Kcal/day for older men and 1600 Kcal/day for women. Health problem arises when intakes are less than 1500 Kcal/day; supplementation is often needed for those who have a severely restricted caloric intake.

Proteins
Proteins

are made up of 22 amino acids of which 13 are produced by the body. Remaining 9 are not made by body and are called essential amino acids. They need to be supplied from food sources.

Proteins-what do they do?

Growth

& maintenance of body tissues, Production of enzymes, hormones, blood, Acid-base balance, fluid & electrolyte balance, transportation of lipids, vitamins, minerals and oxygen around the body.

How do we use protein

Our

bodies make 13 amino acids. Balance 9 are to be supplied from outside source; these are called essential amino acids. It has been observed that on an average we need 1 gram protein per Kg body weight daily to remain healthy, since the body cannot store proteins.

Source of protein
Rice,

Wheat, Lentil, Legumes, Nuts, Beans Vegetables & milk Meat, Fish, Poultry, Egg

Protein Deficiency
The

tissues where protein is heavily used will be weakened, Children will fail to grow properly, You will have digestive disorders due to non-renewal of lining of digestive tract and will suffer from anaemia due to nongeneration of red blood cells, It will cause muscle wasting, hair loss and fluid retention.

Carbohydrates
These are sugar compounds made by plants when they are exposed to light.

Carbohydrates-Types
Simple-With one unit of sugar called monosaccharide and two units of sugar called disaccharide like glucose & sucrose Complex-Also known as polysaccharides such as grains, cereals, vegetables and fruits, Dietary fiber-It is an indigestible form of carbohydrate. It is vital to the body in its role of regulating bowel functions, reducing the risk of intestinal problems and promoting feelings of fullness. Examples Soluble-Fruits, oats, barley, legumes Insoluble-Wheat bran, cereals, vegetables.

What do carbohydrates do?

Carbohydrates

are the bodys most efficient energy source. They keep muscles, brain and other organs running smoothly. However if excess carbohydrates are consumed, they are converted into fat.

Deficiency of carbohydrates
If

sufficient carbohydrates are not consumed, the deficiency is fulfilled by the body by utilizing available protein as energy source. In that event the functions of protein will be jeopardized.

FAT
Fat

is a substance composed of lipids or fatty acids and occur in various forms or consistencies. It is an excellent form of fuel for energy. No more than 25-35% of total daily caloric intake should come from fats (lipids). Mono- and poly-unsaturated fats to be used and saturated fats to be avoided. Essential for Fat-soluble vitamins

FATS
Olive

oil is the best cooking oil. Considering the affordability, next best thing is Rice bran oil which contains maximum qty of Omega 3 fatty acid that does tremendous good to the overall health by protecting from inflammations. Other cooking oils contain lots of Omega 6 fatty acids that contribute to inflammation.

VITAMINS
What

are vitamins? Vitamins are organic, essential nutrients required in varying amounts to perform specific functions that promote growth, reproduction, normal metabolism and maintenance of health & life.

What do vitamins do?

Vitamins

regulate metabolic processes, control cellular functions and reduce the risk of degenerative diseases. However, each individual vitamin has its own daily requirements, food sources, functions, deficiencies and toxicity risks.

MINERALS
WHAT

ARE MINERALS? These are inorganic matter and constitute larger portion of the body than vitamins, up to five percent. There are two classifications of minerals required for health: the macronutrient and the trace minerals. Although needed in small quantities, trace minerals are still essential for human survival.

What do minerals do?

Minerals

are essential in the diet, acting as co-factors of enzymes (enzymes would not exist or function without minerals) and as organizers of the molecular structure of the cells and its membranes. Examples of minerals: Calcium, Phosphorus, Iron, Sodium, Potassium, Magnesium, Manganese, Zinc, Chromium, Selenium, Silicon, Molybdenum, etc.

WATER
What

is water? Water is a colorless, tasteless and nearly odorless liquid essential for plant & animal life. Our body comprises of 60-70% water.

What does water do?

Every

cell in our body needs water to carry out a variety of physiological functions, lubricating and cushioning organs, transporting nutrients, flushing out toxins from the body and participating in many normal chemical reactions.

How much water?

How

much water is needed depends upon the age and muscle & fat content of the body. Muscle tissues have more water than fat tissue. Average male body has proportionately more muscle than the average female body; it also contains more water. For the same reason, a young body generally has more water than an older one.

How do I use water

Everyone

should drink at least eight(240 ml) glasses of water per day and an active person should strive for more. Here is where your water goes each day: 850-1200 ml is lost in breath & perspiration 600-1600 ml is lost in urine 50-200 ml is lost in feces

Degenerative Diseases
What are Degenerative Diseases? These are the diseases that once get into a person, cause steady degeneration over five, ten or twenty years and lead to death or to untold suffering. These are not caused by any germ, bacteria or virus. These diseases viz. Heart diseases, Diabetes, Cancer, Arthritis, Dementia, Macular Degeneration, Fibromyalgia, Obstructive Pulmonary Disease and many such others are caused by erratic oxygen.

Exact causation
Our

body is comprised of billions of cells. Each has a furnace where oxygen burns the food particles whereby energy is released which helps us to carry on activities. This process is known as oxidation. Due to excitation during this process, an electron out of the 4 pairs gets knocked off.

Exact causation
The

contd.

positively charged oxygen atom a Free Radical, cannot remain stable in isolation. It steals an electron from the surrounding. If the victim is a DNA molecule, it undergoes qualitative change and gives rise to unregulated production of cells setting up chain reaction. The result is cancerous growth.

Exact causation
If

contd.

the victim happens to be a cholesterol molecule, its quality changes leading to stickiness. Over a period of time the buildup leads to blockage of blood vessels and we get cardiovascular disease. If on the other hand, the victim happens to be beta cell in the pancreas, the production of insulin gets hampered causing rise in blood sugar which leads to diabetes.

The Solution
Free

Radicals, the enemy inside our body are essentially out of control molecules. Apart from being produced in our body, they get introduced through exposure to air, pollution, UV light, ozone, mercury, junk foods & beverages and even from personal stress. To contain this enemy, solution is ANTIOXIDANTS.

The solution
An

contd.

anti-oxidant is any substance that has the ability to give up an electron to a free radical and balance out the unpaired electron which neutralizes the free radical. Our own bodys defense mechanism creates three major anti-oxidants: Superoxide dismutase, Catalase and Glutathione peroxidase.

The solution
All

contd.

the anti-oxidants that we need, however are not produced by our body. Most of them we get from vegetables & fruits. The common anti-oxidants are Vitamin C, Vitamin E and beta carotene (precursor of Vitamin A). We can obtain numerous other antioxidants from our food; These include

The solution

contd.

Coenzyme Q10,alpha-lipoic acid and the colorful bioflavanoid anti-oxidants. It is important to realize that anti-oxidants work in synergy with one another to disarm free radicals in different areas of the body. Previously, a generation or two ago people ate more whole fresh foods that contained significantly more anti-oxidants than todays diet does.

The solution
But

contd.

as a result of the tremendous increase in the toxins in our environment today, along with the depleted nutrients we receive from our highly processed foods, we are at a disadvantage to fight the free radicals. We need to add Nutritional supplements in our daily intake in order to provide the level of anti-oxidants our bodies need.

The solution
Our

contd.

goal is to have more than enough anti-oxidants to neutralize the free radicals we produce. This can occur only when a complete and balanced army of anti-oxidants is available at all times.

CELLULAR NUTRITION
What is cellular nutrition? In the present day scenario, we have the means of producing nutritional supplements; so we are able to provide these nutrients at optimal levels. Optimal levels are those levels that have been shown to provide a health benefit in the medical literature. These are not RDA (Recommended Daily Allowance) levels. When these nutrients are combined and taken together in supplementation at these optimal levels, the results are simply amazing.

Cellular Nutrition
Cellular

contd.

Nutrition is simply providing all nutrients to the cell at optimal levels. This allows the cell to decide what it really does and does not need. One does not have to worry about determining in which nutrients the cell is deficient. One simply provides all of the important nutrients at optimal levels and let the cells do their work.

Cellular Nutrition
This

contd.

approach corrects any nutritional deficiency over the next few months.

Basic Nutritional Supplement Recommendations

SUPPLEMENT ANTIOXIDANTS VITAMIN A RECOMMENDATION The more and varied the antioxidants, the better. Use of straight Vitamin A is not recommended because of its potential toxicity. In stead supplement with a mixture of mixed carotenoids is recommended. Carotenoids become vitamin A in the body. It is important to have a mixture of carotenoids rather than taking only beta-carotene Beta carotene 10,000 to 15,000 IU Lycopene 1 to 3 mg Lutein/Zeaxanthin 1 to 6 mg Alpha carotene 500 to 800 mcg

CAROTENOIDS

Basic Nutritional Supplement Recommendations contd.

VITAMIN C A mixture of vitamin C is important,especially calcium,potassium,zinc & magnesium ascorbates which are much more potent in handling oxidative stress;1000 to 2000 mg It is important to get a mixture of natural vit E d-alpha tocopherol,d-gamma tocopherol and mixed tocopherol; 400 to 800 IU Bioflavanoids offer a necessary variety of COMPLEX OF potent antioxidants .The amounts may vary,but should include the majority of the following: Rutin, Quercetin,Broccoli,Green Tea,Cruciferous ,Billberry, Phytonutrients, Bromelain

VITAMIN E

BIOFLAVANOID

ALPHA-LIPOLIC ACID

15 to 30 mg

Basic Nutritional Supplement Recommendations contd.

CoQ10 GLUTATHIONE Precursor Nacetyl-L-cysteine 20 to 30 mg 10 to 20 mg 50 to 70 mg

B VITAMINS
(COFACTORS)

Folic acid Vit B1(Thiamin) Vit B2(Riboflavin) Vit B3(Niacin) Vit B5(Pantothenic acid) Vit B6(Pyridoxine) Vit B12(Cobalamin) Biotin

800 to 1000 mcg 20 to 30 mg 25 to 50 mg 30 to 75 mg 80 to 200 mg 20 to 50 mg 100 to 250 mcg 300 to 1000 mcg

Basic Nutritional Supplement Recommendations contd.

MINERAL COMPLEX Calcium 800 to 1500 mg depending on your dietary intake of calcium Magnesium 500 to 800 mg Zinc 20 to 30 mg Chromium 200 to 300 mcg Iron 8 to 10 mg Copper 1 to 3 mg Manganese 3 to 5 mg Vanadium 30 to 100 mcg Iodine 100 to 200 mcg Molybdenum 50 to 100 mcg

ADDITIONAL NUTRIENTS FOR BONE HEALTH

Silicon 3 mg Boron 2-3 mg

Basic Nutritional Supplement Recommendations contd.

OTHER IMPORTANT& ESSENTIAL NUTRIENTS Improved Homocysteine levels and improved brain function Phytonutrients Choline 100 to 200 mg Trimethylglycine 200 to 500 mg Inositol 150 to 250 mg

Lycopene 2/3 serving Tomato Lutein 1 & 1/3 serving Spinach Quercetin 3 & 1/3 serving Apples Ellagic Acid 1 serving of Raspberries Hesperidin 2 Valencia Oranges EGCG 1 & 2/3 serving of Green Tea ( Epigallocatechin gallate)

ESSENTIAL FATS

Cold pressed Flaxseed oil,Walnut,Pumpkin seeds,Fish oil(Salmon)

SPECIFIC OPTIMIZERS FOR THE DEGENERATIVE DISEASES

HEART DISEASE Approx. 100 mg of CoQ10 and phytonutrients (in amounts equivalent to 10 servings of fruits and vegetables) along with some additional magnesium, about 200to 300 mg is recommended daily. It is critical for these patients to take a basic product that contains a mixture of vitamin Es as mentioned in Basic recommendations. If ones homocysteine level does not drop below 7 with just the B vitamins,1-5 g of TMG (Trimethylglycine)is added to the patients regimen. CARDIOMYOPATHY 300-600 mg of CoQ10 is added to the patients regimen along with some additional magnesium and phytonutrients (in amounts equivalent to 10 servings of fruits and vegetables) .Patients will usually see a response within 4 months

Specific optimizers

CoQ10 is very safe and the top researchers in US medical establishments feel comfortable pushing to 600 mg daily if the patient is not responding to the lower doses. However some cardiologists like to perform blood level testing on the amount of CoQ10 in the blood before they begin to recommend higher doses.

Specific optimizers

CANCER It is hard to give a simple formula for all the various cancers. But if there is no evidence of the cancer spreading (or the surgeon believes he totally removed it) phytonutrients (in amounts equivalent to 10 servings of fruits and vegetables) and CoQ10 is added. If the patient has metastatic cancer (cancer thats spread) phytonutrients (in amounts equivalent to 10 servings of fruits and vegetables) is added along with 500-600 mg of CoQ10.Children aged 8 to 15 should take only half of the recommended levels of the basic recommendations and half of the phytonutrients and CoQ10 recommended here.

Specific optimizers

MACULAR DEGENERATION For patients with this condition, phytonutrients (in amounts equivalent to 10 servings of fruits and vegetables) is added to the basic supplements.6-12 mg of additional lutein is also added to the regime. It has been found that if these patients are going to improve, it will occur within the first 4 months. MULTIPLE SCLEROSIS Phytonutrients (in amounts equivalent to 10 servings of fruits and vegetables),200-300 mg of CoQ10 and some additional 500-1000 mg of vitamin C can be helpful in this disease. Patients can notice improvement between 6-9 months. LUPUS AND CROHNS DISEASE Such patients need phytonutrients (in amounts equivalent to 10 servings of fruits and vegetables) and 200 mg of CoQ10 added to the basic supplements. Again,if these patients improve, its usually after about 6 months.

Specific optimizers

OSTEOARTHRITIS 1500-2000 mg of Glucosamine hydrochloride, 600 mg of Omega 3 fatty acid and phytonutrients (in amounts equivalent to 10 servings of fruits and vegetables) is additionally recommended to achieve improvement. RHEUMATOID ARTHRITIS Again 1500-2000 mg of Glucosamine hydrochloride,600 mg of Omega 3 fatty acid,300 mg of CoQ10, phytonutrients (in amounts equivalent to 10 servings of fruits and vegetables) and additional 200 mg of calcium & magnesium is recommended in addition to basic supplements for improvement to be obtained. OSTEOPOROSIS Optimizers are not recommended ; however patients are strongly encouraged to get right levels of vitamin D, Calcium and Magnesium and to be sure they are taking these with food. They are also highly recommended to get involved in weight-bearing exercises of the upper body

Specific optimizers

ASTHMA 300 mg of Omega 3 fatty acid , phytonutrients(in amounts equivalent to 10 servings of fruits and vegetables),(children should take 4 mg per kg body weight per day)along with additional 1000 mg vitamin C(children 200-500 mg),and 200 mg magnesium(children to take additional 100 mg). EMPHYSEMA The basic nutrients are usually sufficient.300 mg of Omega 3 fatty acid, phytonutrients(in amounts equivalent to 10 servings of fruits and vegetables) along with additional vitamin C and magnesium are given based on the condition. ALZHEIMERS DEMENTIA and PARKINSONS DISEASE There is good medical evidence that the progression of the Alzheimers dementia and Parkinsons disease may be slowed

Specific optimizers

with adding 600 mg of Omega 3 fatty acid and phytonutrients (in amounts equivalent to 10 servings of fruits and vegetables). DIABETES MELLITUS Phytonutrients (in amounts equivalent to 10 servings of fruits and vegetables) is added to the regime.The cellular nutrition listed previously definitely provides everything else the body needs. CHRONIC FATIGUE/FIBROMYALGIA Phytonutrients (in amounts equivalent to 10 servings of fruits and vegetables) along with 100-200 mg of CoQ10 and 300 mg of Omega 3 fatty acid are added to the basic supplementary program. Sometimes phytonutrients are increased to double the quantity daily in order to capture this disease. Once patients are responding favourably ,the dose can be decreased to a lower maintenance level.

Acknowledgement I.

I remember with utmost deference the path-breaking discoveries and contributions the following medical practitioners, research scientists as well as visionaries made towards formulating the concept of CELLULAR NUTRITION which is the gateway to healthy and happy living devoid of dreaded degenerative diseases :

Acknowledgement I
Dr.

contd.

Linus Pauling Immune System Dr. Allen Cooper Author of antioxidant revolution and creator of aerobic exercises. Dr. Daniel Steinberg Control of LDL cholesterol with antioxidants Dr. Marco Diaz Control of coronary artery disease with antioxidants

Acknowledgement I contd.
Kilmer McCully Study of Homocysteine Dr Benjamin Castle Champion of homocysteine study Dr. Meir Stampfer Role of homocysteine on heart disease Dr. Jacob Selhub Role of homocysteine on carotid artery stenosis
Dr.

Acknowledgement I contd.
Karl Folkers,Dr Baggio ,Dr Langsjoen Efficacy and safety of use of CoQ10 in patients with end stage heart failure. Dr Donald Malins Change of DNA structure due to free-radical damage Dr Gladys Block Benefit of fruits and vegetables to reduce cancer risk Dr Harinder Garewal Anti-oxidants for chemo-prevention.
Dr

Acknowledgement I contd.
Prasad, Dr Arun Kumar High dosages of multiple anti-oxidant vitamins: Essential ingredients in improving the efficacy of the Stahdard Cancer Therapy. Dr Karl Heinz Schmidt - Immune System. Sri D. Bagchi -Free radicals and grapeseed proanthocyanidin extract:Importance in human health & disease prevention.
Dr.Kedar

Acknowledgment II
1.

2.

3.

4.

Krauses Food, Nutrition and diet therapy What your doctor does not know about nutrition medicine, may be killing you Dr Ray D Strand Principles of Nutrition Nutrilite Health Institute, California. Optimal Health Revolution Dr Duke Johnson

Acknowledgment II contd.
5.

6.
7. 8.

9.
10. 11. 12.

New England Journal of Medicine Journal of American Medical Association American Journal of Clinical Nutrition Journal of Nutritional Medicine American Journal of Cardiology Novartis Foundation Symposium Lancet Annals of the New York Academy of Science

Acknowledgment II contd.
13.

14.

Journal of the American College of Nutrition New England Journal of Medicine

Acknowledgment III
I am extremely thankful to the Director, Shri N.B Jayaprakash , of the Dignity Foundation, Bangalore Chapter for providing me an opportunity to address their honorable members and making this presentation before them.

SHUBHAM ASTHU